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Diseases

Genetic and Rare Diseases Information Center (GARD)

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Pityriasis lichenoides et varioliformis acuta


Other Names for this Disease
  • Mucha-Habermann disease
  • PLEVA
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Your Question

I was diagnosed with Mucha-Habermann disease six months ago. I have tried many different treatments, but nothing has made a difference. Can you provide information on treatments for this condition?

Our Answer

We have identified the following information that we hope you find helpful. If you still have questions, please contact us.

How might pityriasis lichenoides et varioliformis acuta (PLEVA) be treated?

Many treatments have been reported for PLEVA, although their effectiveness varies among people with this condition. Depending on the severity of PLEVA, treatment may include increased sun exposure, topical steroids, topical immunomodulators (such as tacrolimus or pimecrolimus), oral antibiotics (such as erythromycin or tetracycline), phototherapy, systemic steroidsmethotrexate, acitretin, dapsone, ciclosporin, or etanercept. PLEVA may not always respond to treatment and relapses often occur when treatment is discontinued.[1][2]
Last updated: 5/2/2012

References
  • Pityriasis lichenoides. New Zealand Dermatological Society Web site. 2011; http://dermnetnz.org/scaly/pityriasis-lichenoides.html. Accessed 1/3/2012.
  • Nikkels AF, Gillard P, Piérard GE. Etanercept in therapy multiresistant overlapping pityriasis lichenoides. J Drugs Dermatol. 2008 Oct;7(10):990-2. http://www.ncbi.nlm.nih.gov/pubmed/19112768 .