FDA Approved Medical Products for:

Pulmonary arterial hypertension

The table(s) below may not be an exhaustive list of drugs or products used to treat this condition. There may be other products available that are not considered orphan products.

Generic Name Riociguat
Trade Name
(Manufacturer Name)
Adempas
(Bayer HealthCare Pharmaceuticals, Inc.)
Indication
The FDA has approved this product to be used in this manner.
Treatment of adults with pulmonary arterial hypertension (PAH) WHO Group 1, to improve exercise capacity, WHO functional class and to delay clinical worsening.
More Information about this product Drug Information Portal

Generic Name Epoprostenol
Trade Name
(Manufacturer Name)
Flolan®
(Glaxo Wellcome Inc.)
Indication
The FDA has approved this product to be used in this manner.
Long-term intravenous treatment of primary pulmonary hypertension in NYHA Class III and Class IV patients.
More Information about this product Drug Information Portal

Generic Name Ambrisentan
Trade Name
(Manufacturer Name)
Letairis®
(Gilead Colorado)
Indication
The FDA has approved this product to be used in this manner.
Treatment of pulmonary arterial hypertension (WHO group I) in patients with WHO class II or III symptoms to improve exercise capacity and delay clinical worsening
More Information about this product Drug Information Portal

Generic Name macitentan
Trade Name
(Manufacturer Name)
Opsumit
(Actelion Pharmaceuticals Ltd)
Indication
The FDA has approved this product to be used in this manner.
Treatment of pulmonary arterial hypertension (PAH, WHO Group 1) to delay disease progression. Disease progression included: death, initiation of intravenous (IV) or subcutaneous prostanoids, or clinical worsening of PAH (decreased 6-minute walk distance, worsened PAH symptoms and need for additional PAH treatment). Opsumit also reduced hospitalization for PAH.
More Information about this product Drug Information Portal

Generic Name Treprostinil
Trade Name
(Manufacturer Name)
Remodulin®
(United Therapeutics Corp.)
Indication
The FDA has approved this product to be used in this manner.
Treatment of pulmonary arterial hypertension.
More Information about this product Drug Information Portal

Generic Name Bosentan
Trade Name
(Manufacturer Name)
Tracleer®
(Actelion Life Sciences Ltd.)
Indication
The FDA has approved this product to be used in this manner.
Treatment of pulmonary arterial hypertension.
More Information about this product Drug Information Portal
Medline Plus Health Information

Generic Name Iloprost solution for infusion
Trade Name
(Manufacturer Name)
Ventavis®
(Acetlion)
Indication
The FDA has approved this product to be used in this manner.
Treatment of pulmonary arterial hypertension (WHO Group I) in patients with NYHA Class III or IV symptoms
More Information about this product Drug Information Portal