{"Name":"Aneurysm, intracranial berry, 2","DiseaseID__c":"GARD:0010033","id":10033,"encodedName":"aneurysm-intracranial-berry-2","IsDeleted":false,"Disease_Name_Full__c":"Aneurysm, intracranial berry, 2","Xref_IDs__c":"C1837894; C536360; DOID:0080965; MEDGEN:325285; MONDO:0012053; OMIM:608542","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":0,"Description_Source__c":"OMIM:608542","Disease_Description__c":"Intracranial berry aneurysms are saccular outpouchings of the intracranial arteries, most commonly at arterial bifurcations, characterized by arterial wall remodeling. Most cases of ruptured intracranial berry aneurysms result in a subarachnoid hemorrhage, associated with high morbidity and mortality (summary by {2:van der Voet et al., 2004}).\\n\\nFor a discussion of genetic heterogeneity of intracranial berry aneurysm, see ANIB1 ({105800}).","GARD_Name__c":"Aneurysm, intracranial berry, 2","GARD_Synonym__c":"anib2","Curated_Disease_Description_Source__c":"MEDGEN:C1837894","Curated_Disease_Description__c":"Intracranial berry aneurysms are saccular outpouchings of the intracranial arteries, most commonly at arterial bifurcations, characterized by arterial wall remodeling. Most cases of ruptured intracranial berry aneurysms result in a subarachnoid hemorrhage, associated with high morbidity and mortality (summary by van der Voet et al., 2004).For a discussion of genetic heterogeneity of intracranial berry aneurysm, see ANIB1 (105800).","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"OMIM:608542","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0012053","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Intracranial berry aneurysms are saccular outpouchings of the intracranial arteries, most commonly at arterial bifurcations, characterized by arterial wall remodeling. Most cases of ruptured intracranial berry aneurysms result in a subarachnoid hemorrhage, associated with high morbidity and mortality (summary by van der Voet et al., 2004).For a discussion of genetic heterogeneity of intracranial berry aneurysm, see ANIB1 (105800).","Curated_Disease_Description_Source__c":"MEDGEN:C1837894","GARD_Synonym__c":"anib2","Name":"Aneurysm, intracranial berry, 2","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"The Aneurysm and AVM Foundation","Website__c":"https://taafonline.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Vascular Neurology","Tag_Category__c":"Specialist","curated_tag_name":"Vascular neurology"},{"Tag_Name__c":"Vascular Medicine","Tag_Category__c":"Specialist","curated_tag_name":"Vascular diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0010033","Source__c":"RareSource"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0080965","Source__c":"MONDO:0012053","Xref__c":"DOID:0080965"},{"URL__c":"https://www.omim.org/entry/608542","Source__c":"C1837894; MONDO:0012053","Xref__c":"OMIM:608542"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C536360","Source__c":"MONDO:0012053","Xref__c":"C536360"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1837894","Source__c":"C1837894","Xref__c":"C1837894"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=325285","Source__c":"C1837894","Xref__c":"MEDGEN:325285"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0012053","Source__c":"GARD:0010033","Xref__c":"MONDO:0012053"}],"GARD_Disease_Feature__c":[{"Provided_By__c":"OMIM:608542","Feature__r":{"HPO_Description__c":"Hemorrhage occurring between the arachnoid mater and the pia mater.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002138","HPO_Synonym__c":"Subarachnoid hemorrhage","HPO_Name__c":"Subarachnoid hemorrhage","Feature_System__c":"Nervous System; Cardiovascular System; Blood and Blood-Forming Tissue","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"OMIM:608542","Feature__r":{"HPO_Description__c":"A small, sac-like aneurysm (outpouching) of a cerebral blood vessel.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0007029","HPO_Synonym__c":"Cerebral saccular aneurysm","HPO_Name__c":"Cerebral berry aneurysm","Feature_System__c":"Nervous System; Cardiovascular System","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Vascular Neurology","Vascular Medicine"]},"synonyms":["anib2"]}