{"Name":"Juvenile paralysis agitans of Hunt","DiseaseID__c":"GARD:0010359","id":10359,"encodedName":"juvenile-paralysis-agitans-of-hunt","IsDeleted":false,"Disease_Name_Full__c":"Juvenile paralysis agitans of Hunt","Xref_IDs__c":"43647007; C0238344; C562469; MEDGEN:66768; MONDO:0008193; OMIM:168100","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"OMIM:168100","Disease_Description__c":null,"GARD_Name__c":"Juvenile paralysis agitans of Hunt","GARD_Synonym__c":"neostriatal syndrome; paleostriatal syndrome; pallidal atrophy; pallidal syndrome; paralysis agitans, juvenile, of hunt; parkinson disease, juvenile, of hunt","Curated_Disease_Description_Source__c":"OMIM:168100","Curated_Disease_Description__c":"Paralysis agitans, juvenile, of hunt is a disorder with typical parkinsonism beginning in the teens or earlier. Symptoms include tremor, masklike facies, bradykinesia, dysarthria, and rigidity. Progression is very slow. The substantia nigra is normal, but degeneration and loss of large cells of the lenticular nuclei may occur. Gait disturbances ('walking on the ball of the foot') and tremor in the hands may present during childhood. Flexion dystonia of the fingers and fixed facial expression may occur by late adulthood in some cases and eventual immobility may be observed.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"OMIM:168100","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0008193","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Paralysis agitans, juvenile, of hunt is a disorder with typical parkinsonism beginning in the teens or earlier. Symptoms include tremor, masklike facies, bradykinesia, dysarthria, and rigidity. Progression is very slow. The substantia nigra is normal, but degeneration and loss of large cells of the lenticular nuclei may occur. Gait disturbances ('walking on the ball of the foot') and tremor in the hands may present during childhood. Flexion dystonia of the fingers and fixed facial expression may occur by late adulthood in some cases and eventual immobility may be observed.","Curated_Disease_Description_Source__c":"OMIM:168100","GARD_Synonym__c":"neostriatal syndrome; paleostriatal syndrome; pallidal atrophy; pallidal syndrome; paralysis agitans, juvenile, of hunt; parkinson disease, juvenile, of hunt","Name":"Juvenile paralysis agitans of Hunt","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Parkinson & Movement Disorder Alliance","Website__c":"https://www.pmdalliance.org/"},{"Account_Name__c":"International Parkinson and Movement Disorder Society","Website__c":"https://www.movementdisorders.org/"},{"Account_Name__c":"Michael J. Fox Foundation for Parkinson's Research","Website__c":"https://www.michaeljfox.org/"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=43647007","Source__c":"C0238344; MONDO:0008193","Xref__c":"43647007"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0238344","Source__c":"C0238344","Xref__c":"C0238344"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C562469","Source__c":"MONDO:0008193","Xref__c":"C562469"},{"URL__c":"https://www.omim.org/entry/168100","Source__c":"C0238344; MONDO:0008193","Xref__c":"OMIM:168100"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=66768","Source__c":"C0238344","Xref__c":"MEDGEN:66768"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0008193","Source__c":"GARD:0010359","Xref__c":"MONDO:0008193"}],"tags":{},"synonyms":["neostriatal syndrome"," paleostriatal syndrome"," pallidal atrophy"," pallidal syndrome"," paralysis agitans, juvenile, of hunt"," parkinson disease, juvenile, of hunt"]}