{"Name":"Ovarian small cell carcinoma","DiseaseID__c":"GARD:0010411","id":10411,"encodedName":"ovarian-small-cell-carcinoma","IsDeleted":false,"Disease_Name_Full__c":"Ovarian small cell carcinoma","Xref_IDs__c":"C2212006; C27390; DOID:6179; MEDGEN:389177; MONDO:0003795; ORPHA:370396","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":4,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":4,"Description_Source__c":"MONDO:0003795","Disease_Description__c":"A carcinoma that arises from the ovary and is characterized by the presence of small malignant cells. It includes small cell carcinoma, hypercalcemic type and small cell carcinoma, pulmonary type.","GARD_Name__c":"Ovarian small cell carcinoma","GARD_Synonym__c":"ovarian small cell cancer; ovarian small cell nec; ovarian small cell neuroendocrine carcinoma; ovary small cell carcinoma; scco; small cell carcinoma of ovary; small cell carcinoma of the ovary; small cell ovarian carcinoma","Curated_Disease_Description_Source__c":"GARD:0010411","Curated_Disease_Description__c":"Ovarian small cell carcinoma is a rare form of ovarian cancer that typically occurs in young women. It is typically an aggressive cancer that can spread (metastasize) to other parts of the body. There are two types of Ovarian small cell carcinoma: hypercalcemic and pulmonary. Approximately 2/3 of individuals with Ovarian small cell carcinoma have the hypercalcemic type. Symptoms are fairly nonspecific and are similar to other types of ovarian cancer. Symptoms may include: bloating, pelvic or abdominal pain, and appetite changes.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at a variety of ages","SourceID__c":"ORPHA:370396","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0003795","ORPHANET_ID__c":"ORPHA:370396","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Carcinoma de células pequeñas del ovario","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"carcinoma de células pequeñas del ovario","Spanish_GARD_Synonym__c":"carcinoma ovárico de células pequeñas; scco","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Ovarian small cell carcinoma is a rare form of ovarian cancer that typically occurs in young women. It is typically an aggressive cancer that can spread (metastasize) to other parts of the body. There are two types of Ovarian small cell carcinoma: hypercalcemic and pulmonary. Approximately 2/3 of individuals with Ovarian small cell carcinoma have the hypercalcemic type. Symptoms are fairly nonspecific and are similar to other types of ovarian cancer. Symptoms may include: bloating, pelvic or abdominal pain, and appetite changes.","Curated_Disease_Description_Source__c":"GARD:0010411","GARD_Synonym__c":"ovarian small cell cancer; ovarian small cell nec; ovarian small cell neuroendocrine carcinoma; ovary small cell carcinoma; scco; small cell carcinoma of ovary; small cell carcinoma of the ovary; small cell ovarian carcinoma","Name":"Ovarian small cell carcinoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"National Ovarian Cancer Coalition","Website__c":"https://ovarian.org/"},{"Account_Name__c":"Ovarian Cancer Research Alliance","Website__c":"https://ocrahope.org"},{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"},{"Account_Name__c":"Minnesota Ovarian Cancer Alliance","Website__c":"http://mnovarian.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Urogenital Disorders","Tag_Category__c":"Disease Category","category_description":"Urinary and reproductive diseases affect the kidneys, ureters, bladder, urethra, or the reproductive organs.","curated_tag_name":"Urinary and reproductive diseases"},{"Tag_Name__c":"Obstetrics / Gynecology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Rare gynecological tumor","Tag_Category__c":"Account;Specialist","curated_tag_name":"Gynecological tumors"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adolescent","Provided_By__c":"ORPHA:370396"},{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:370396"},{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:370396"},{"Age_At_Onset__c":"Infancy","Provided_By__c":"ORPHA:370396"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0010411","Source__c":"RareSource"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C27390","Source__c":"C2212006; MONDO:0003795","Xref__c":"C27390"},{"URL__c":"https://www.orpha.net/en/disease/detail/370396","Source__c":"C2212006; MONDO:0003795; ORPHA:370396","Xref__c":"ORPHA:370396"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C2212006","Source__c":"C2212006","Xref__c":"C2212006"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=389177","Source__c":"C2212006","Xref__c":"MEDGEN:389177"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A6179","Source__c":"MONDO:0003795","Xref__c":"DOID:6179"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=770601003","Source__c":"C2212006","Xref__c":"770601003"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0003795","Source__c":"GARD:0010411","Xref__c":"MONDO:0003795"}],"GARD_Disease_Gene__c":[{"GeneSymbol__c":"SMARCA4","GHR_URL__c":"https://medlineplus.gov/genetics/gene/smarca4","Gene_Type__c":"protein-coding gene","Causal_Gene__c":true}],"tags":{"Specialist":["Cancer - Oncologist","Obstetrics / Gynecology","Rare gynecological tumor","Pediatrics"],"Disease Category":["Cancer","Urogenital Disorders"],"Account":["Rare gynecological tumor"]},"synonyms":["ovarian small cell cancer"," ovarian small cell nec"," ovarian small cell neuroendocrine carcinoma"," ovary small cell carcinoma"," scco"," small cell carcinoma of ovary"," small cell carcinoma of the ovary"," small cell ovarian carcinoma"]}