{"Name":"Goblet cell carcinoma","DiseaseID__c":"GARD:0010414","id":10414,"encodedName":"goblet-cell-carcinoma","IsDeleted":false,"Disease_Name_Full__c":"Goblet cell carcinoma","Xref_IDs__c":"C0205695; C201135; C3689; MEDGEN:60007; MONDO:0018017; ORPHA:329984","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0018017","Disease_Description__c":"Goblet cell carcinoma (GCC) is an aggressive type of endocrine tumor of the appendix (see this term) presenting equally in males and females in the fifth decade of life and manifesting with a palpable mass and abdominal pain or acute appendicitis. Metastasis to the ovaries, peritoneum or right colon has usually already occurred in half of patients at the time of diagnosis.","GARD_Name__c":"Goblet cell carcinoma","GARD_Synonym__c":"appendix adenocarcinoid tumor; appendix adenocarcinoid tumour; appendix goblet cell carcinoid; appendix goblet cell carcinoid tumor; appendix goblet cell carcinoid tumour; appendix mixed carcinoid-adenocarcinoma; carcinoma of goblet cell; gcc; goblet cell adenocarcinoid; goblet cell adenocarcinoma; goblet cell carcinoid; goblet cell carcinoid of appendix; goblet cell carcinoid of the appendix; goblet cell carcinoid tumor; goblet cell carcinoid tumour; goblet cell tumor; goblet cell tumour; mucinous carcinoid; mucinous carcinoid tumor; mucinous carcinoid tumour; mucocarcinoid tumor; mucocarcinoid tumor, malignant","Curated_Disease_Description_Source__c":"GARD:0010414","Curated_Disease_Description__c":"Goblet cell carcinoid (GCC) is a rare tumor normally occurring in the appendix which displays features of both a neuroendocrine tumor and a more aggressive form of cancer known as an adenocarcinoma. People with this tumor may develop acute appendicitis, abdominal pain, and diarrhea.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:329984","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0018017","ORPHANET_ID__c":"ORPHA:329984","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Carcinoma de células caliciformes","Spanish_Description_Source__c":"ORPHA:329984","Spanish_Description__c":"El tumor carcinoide de células caliciformes (CCG, por sus siglas en inglés) es un tipo agresivo de tumor endocrino del apéndice que se presenta por igual en hombres y mujeres en la quinta década de la vida y que se manifiesta con una masa palpable y dolor abdominal o apendicitis aguda. Generalmente en la mitad de los pacientes ya se han producido metástasis en los ovarios, el peritoneo o el colon derecho en el momento del diagnóstico.","Spanish_Disease_Name__c":"carcinoma de células caliciformes","Spanish_GARD_Synonym__c":"célula caliciforme adenocarcinoide; célula caliciforme carcinoide; gcc; tumor de células caliciformes","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Goblet cell carcinoid (GCC) is a rare tumor normally occurring in the appendix which displays features of both a neuroendocrine tumor and a more aggressive form of cancer known as an adenocarcinoma. People with this tumor may develop acute appendicitis, abdominal pain, and diarrhea.","Curated_Disease_Description_Source__c":"GARD:0010414","GARD_Synonym__c":"appendix adenocarcinoid tumor; appendix adenocarcinoid tumour; appendix goblet cell carcinoid; appendix goblet cell carcinoid tumor; appendix goblet cell carcinoid tumour; appendix mixed carcinoid-adenocarcinoma; carcinoma of goblet cell; gcc; goblet cell adenocarcinoid; goblet cell adenocarcinoma; goblet cell carcinoid; goblet cell carcinoid of appendix; goblet cell carcinoid of the appendix; goblet cell carcinoid tumor; goblet cell carcinoid tumour; goblet cell tumor; goblet cell tumour; mucinous carcinoid; mucinous carcinoid tumor; mucinous carcinoid tumour; mucocarcinoid tumor; mucocarcinoid tumor, malignant","Name":"Goblet cell carcinoma","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"},{"Account_Name__c":"Carcinoid Cancer Foundation","Website__c":"https://www.carcinoid.org/"},{"Account_Name__c":"Neuroendocrine Tumor Research Foundation","Website__c":"https://netrf.org/"},{"Account_Name__c":"Appendix Cancer/Pseudomyxoma Peritonei Research Foundation","Website__c":"https://acpmp.org/"},{"Account_Name__c":"Canadian NeuroEndocrine Tumour Society","Website__c":"https://cnets.ca/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Endocrine","Tag_Category__c":"Disease Category;Specialist","category_description":"Endocrine diseases affect hormone production or how the body responds to a specific hormone(s).","curated_tag_name":"Endocrine diseases"},{"Tag_Name__c":"Gastroenterology","Tag_Category__c":"Disease Category;Specialist","category_description":"Gastrointestinal diseases, or digestive diseases, affect the esophagus, stomach, small intestine, large intestine, liver, gallbladder, or pancreas.","curated_tag_name":"Gastrointestinal diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:329984"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0205695","Source__c":"C0205695","Xref__c":"C0205695"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=60007","Source__c":"C0205695","Xref__c":"MEDGEN:60007"},{"URL__c":"https://www.orpha.net/en/disease/detail/329984","Source__c":"C0205695; MONDO:0018017; ORPHA:329984","Xref__c":"ORPHA:329984"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3689","Source__c":"MONDO:0018017","Xref__c":"C3689"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018017","Source__c":"GARD:0010414","Xref__c":"MONDO:0018017"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C201135","Source__c":"C0205695","Xref__c":"C201135"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=31396002","Source__c":"C0205695","Xref__c":"31396002"}],"tags":{"Specialist":["Cancer - Oncologist","Endocrine","Gastroenterology"],"Disease Category":["Cancer","Endocrine","Gastroenterology"]},"synonyms":["appendix adenocarcinoid tumor"," appendix adenocarcinoid tumour"," appendix goblet cell carcinoid"," appendix goblet cell carcinoid tumor"," appendix goblet cell carcinoid tumour"," appendix mixed carcinoid-adenocarcinoma"," carcinoma of goblet cell"," gcc"," goblet cell adenocarcinoid"," goblet cell adenocarcinoma"," goblet cell carcinoid"," goblet cell carcinoid of appendix"," goblet cell carcinoid of the appendix"," goblet cell carcinoid tumor"," goblet cell carcinoid tumour"," goblet cell tumor"," goblet cell tumour"," mucinous carcinoid"," mucinous carcinoid tumor"," mucinous carcinoid tumour"," mucocarcinoid tumor"," mucocarcinoid tumor, malignant"]}