{"Name":"Langerhans cell sarcoma","DiseaseID__c":"GARD:0010491","id":10491,"encodedName":"langerhans-cell-sarcoma","IsDeleted":false,"Disease_Name_Full__c":"Langerhans cell sarcoma","Xref_IDs__c":"128814006; 724649000; C1260327; C6921; D054752; DOID:7146; MEDGEN:266041; MONDO:0019480; ORPHA:86897","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0019480","Disease_Description__c":"A neoplastic proliferation of Langerhans cells with overtly malignant cytologic features. It can be considered a higher grade variant of Langerhans cell histiocytosis (LCH) and it can present de novo or progress from antecedent LCH. (WHO, 2001)","GARD_Name__c":"Langerhans cell sarcoma","GARD_Synonym__c":"sarcoma of langerhans cell","Curated_Disease_Description_Source__c":"MONDO:0019480","Curated_Disease_Description__c":"A neoplastic proliferation of Langerhans cells with overtly malignant cytologic features. It can be considered a higher grade variant of Langerhans cell histiocytosis (LCH) and it can present de novo or progress from antecedent LCH. (WHO, 2001)","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:86897","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0019480","ORPHANET_ID__c":"ORPHA:86897","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Sarcoma de células de langerhans","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"sarcoma de células de langerhans","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A neoplastic proliferation of Langerhans cells with overtly malignant cytologic features. It can be considered a higher grade variant of Langerhans cell histiocytosis (LCH) and it can present de novo or progress from antecedent LCH. (WHO, 2001)","Curated_Disease_Description_Source__c":"MONDO:0019480","GARD_Synonym__c":"sarcoma of langerhans cell","Name":"Langerhans cell sarcoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Histiocytosis Association","Website__c":"https://www.histio.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Hematology","Tag_Category__c":"Disease Category;Specialist","category_description":"Blood diseases affect the blood or blood-forming organs, including red blood cells, white blood cells, platelets, plasma, and bone marrow.","curated_tag_name":"Blood diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:86897"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A7146","Source__c":"MONDO:0019480","Xref__c":"DOID:7146"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C054752","Source__c":"C1260327; MONDO:0019480","Xref__c":"D054752"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=266041","Source__c":"C1260327","Xref__c":"MEDGEN:266041"},{"URL__c":"https://www.orpha.net/en/disease/detail/86897","Source__c":"C1260327; MONDO:0019480; ORPHA:86897","Xref__c":"ORPHA:86897"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=724649000","Source__c":"C1260327; MONDO:0019480","Xref__c":"724649000"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1260327","Source__c":"C1260327","Xref__c":"C1260327"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C6921","Source__c":"C1260327; MONDO:0019480","Xref__c":"C6921"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=128814006","Source__c":"C1260327","Xref__c":"128814006"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019480","Source__c":"GARD:0010491","Xref__c":"MONDO:0019480"}],"tags":{"Specialist":["Cancer - Oncologist","Hematology","Pediatrics"],"Disease Category":["Cancer","Hematology"]},"synonyms":["sarcoma of langerhans cell"]}