{"Name":"Appendix adenocarcinoma","DiseaseID__c":"GARD:0010564","id":10564,"encodedName":"appendix-adenocarcinoma","IsDeleted":false,"Disease_Name_Full__c":"Appendix adenocarcinoma","Xref_IDs__c":"413445002; C0238003; C7718; DOID:3608; MEDGEN:65942; MONDO:0006087","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0006087","Disease_Description__c":"A carcinoma that arises from glandular epithelial cells of the vermiform appendix.","GARD_Name__c":"Appendix adenocarcinoma","GARD_Synonym__c":"adenocarcinoma of appendix; adenocarcinoma of the appendix; appendiceal adenocarcinoma; vermiform appendix adenocarcinoma","Curated_Disease_Description_Source__c":"GARD:0010564","Curated_Disease_Description__c":"Cancer of the appendix is very rare and is typically found incidentally during appendectomies, in about 1% of the cases. According to a report published by the National Cancer Institute, using the Surveillance, Epidemiology, and End Results (SEER) database, appendix cancer account for about 0.4% of gastrointestinal tumors. There are several subytpes. The most common is the carcinoid type (66% of the total), with cyst-adenocarcinoma accounting for 20% and adenocarcinoma accounting for 10%. Then there are the rare forms of cancers which include adenocarcinoid, signet ring, non-Hodgkin's lymphoma, ganglioneuroma, and pheochromocytoma. Benign primary tumors are mainly 'mucinous epithelial neoplasms', also called adenomas, cystadenoma, and benign neoplastic mucocele. Adenocarcinoma of the appendix is a epithelial cancer of the appendix. The term 'epithelium' refers to cells that line hollow organs and glands and those that make up the outer surface of the body. Epithelial cells help to protect or enclose organs. Some produce mucus or other secretions.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0006087","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Cancer of the appendix is very rare and is typically found incidentally during appendectomies, in about 1% of the cases. According to a report published by the National Cancer Institute, using the Surveillance, Epidemiology, and End Results (SEER) database, appendix cancer account for about 0.4% of gastrointestinal tumors. There are several subytpes. The most common is the carcinoid type (66% of the total), with cyst-adenocarcinoma accounting for 20% and adenocarcinoma accounting for 10%. Then there are the rare forms of cancers which include adenocarcinoid, signet ring, non-Hodgkin's lymphoma, ganglioneuroma, and pheochromocytoma. Benign primary tumors are mainly 'mucinous epithelial neoplasms', also called adenomas, cystadenoma, and benign neoplastic mucocele. Adenocarcinoma of the appendix is a epithelial cancer of the appendix. The term 'epithelium' refers to cells that line hollow organs and glands and those that make up the outer surface of the body. Epithelial cells help to protect or enclose organs. Some produce mucus or other secretions.","Curated_Disease_Description_Source__c":"GARD:0010564","GARD_Synonym__c":"adenocarcinoma of appendix; adenocarcinoma of the appendix; appendiceal adenocarcinoma; vermiform appendix adenocarcinoma","Name":"Appendix adenocarcinoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"},{"Account_Name__c":"Cancer Hope Network","Website__c":"https://www.cancerhopenetwork.org/"},{"Account_Name__c":"Rare Cancer Alliance","Website__c":"https://www.rare-cancer.org/"},{"Account_Name__c":"Cancer.net","Website__c":"https://www.cancer.net/"},{"Account_Name__c":"Appendix Cancer/Pseudomyxoma Peritonei Research Foundation","Website__c":"https://acpmp.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=413445002","Source__c":"C0238003; MONDO:0006087","Xref__c":"413445002"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=65942","Source__c":"C0238003","Xref__c":"MEDGEN:65942"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0238003","Source__c":"C0238003","Xref__c":"C0238003"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A3608","Source__c":"MONDO:0006087","Xref__c":"DOID:3608"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C7718","Source__c":"C0238003; MONDO:0006087","Xref__c":"C7718"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0006087","Source__c":"GARD:0010564","Xref__c":"MONDO:0006087"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["adenocarcinoma of appendix"," adenocarcinoma of the appendix"," appendiceal adenocarcinoma"," vermiform appendix adenocarcinoma"]}