{"Name":"Anaplastic oligoastrocytoma","DiseaseID__c":"GARD:0010637","id":10637,"encodedName":"anaplastic-oligoastrocytoma","IsDeleted":false,"Disease_Name_Full__c":"Anaplastic oligoastrocytoma","Xref_IDs__c":"253072003; C0431108; C6959; MEDGEN:96556; MONDO:0016703; ORPHA:251663","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0016703","Disease_Description__c":"An oligoastrocytoma characterized by the presence of increased cellularity, nuclear atypia, pleomorphism, and high mitotic activity.","GARD_Name__c":"Anaplastic oligoastrocytoma","GARD_Synonym__c":"amoa; anaplastic mixed glioma; who grade iii mixed glioma","Curated_Disease_Description_Source__c":"GARD:0010637","Curated_Disease_Description__c":"Anaplastic oligoastrocytoma is a brain tumor that forms when two types of cells in the brain, called oligodendrocytes and astrocytes, rapidly increase in number to form a mass. These brain cells are known as glial cells, which normally protect and support nerve cells in the brain. Because an oligoastrocytoma is made up of a combination of two cell types, it is known as a mixed glioma. An oligoastrocytoma is described as anaplastic when the tumor grows quickly and the cancer cells within the tumor have the potential to spread into surrounding brain tissue or to more distant parts of the body. The exact cause of this condition is unknown.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:251663","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0016703","ORPHANET_ID__c":"ORPHA:251663","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Oligoastrocitoma anaplásico","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"oligoastrocitoma anaplásico","Spanish_GARD_Synonym__c":"amoa","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Anaplastic oligoastrocytoma is a brain tumor that forms when two types of cells in the brain, called oligodendrocytes and astrocytes, rapidly increase in number to form a mass. These brain cells are known as glial cells, which normally protect and support nerve cells in the brain. Because an oligoastrocytoma is made up of a combination of two cell types, it is known as a mixed glioma. An oligoastrocytoma is described as anaplastic when the tumor grows quickly and the cancer cells within the tumor have the potential to spread into surrounding brain tissue or to more distant parts of the body. The exact cause of this condition is unknown.","Curated_Disease_Description_Source__c":"GARD:0010637","GARD_Synonym__c":"amoa; anaplastic mixed glioma; who grade iii mixed glioma","Name":"Anaplastic oligoastrocytoma","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:251663"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0010637","Source__c":"RareSource"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0431108","Source__c":"C0431108","Xref__c":"C0431108"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C6959","Source__c":"C0431108; MONDO:0016703","Xref__c":"C6959"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=96556","Source__c":"C0431108","Xref__c":"MEDGEN:96556"},{"URL__c":"https://www.orpha.net/en/disease/detail/251663","Source__c":"C0431108; MONDO:0016703; ORPHA:251663","Xref__c":"ORPHA:251663"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0016703","Source__c":"GARD:0010637","Xref__c":"MONDO:0016703"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=253072003","Source__c":"C0431108","Xref__c":"253072003"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C129324","Source__c":"C0431108","Xref__c":"C129324"}],"tags":{"Specialist":["Cancer - Oncologist","Neurology"],"Disease Category":["Cancer","Neurology"]},"synonyms":["amoa"," anaplastic mixed glioma"," who grade iii mixed glioma"]}