{"Name":"Pudendal neuralgia","DiseaseID__c":"GARD:0010713","id":10713,"encodedName":"pudendal-neuralgia","IsDeleted":false,"Disease_Name_Full__c":"Pudendal neuralgia","Xref_IDs__c":"427972000; C1997249; D060545; MEDGEN:372681; MONDO:0018957; ORPHA:60039","USA_Estimate__c":"200,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"800,000 to 5,000,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":6,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0018957","Disease_Description__c":"A rare, acquired peripheral neuropathy characterized by chronic neuropathic pain involving the sensory territory of the pudendal nerve (from clitoris to anus or from penis to anus) aggravated by sitting. It is often associated with pelvic dysfunction.","GARD_Name__c":"Pudendal neuralgia","GARD_Synonym__c":"alcock syndrome; neuralgia of pudendal nerve; pudendal algia; pudendal nerve entrapment syndrome; pudendal nerve neuralgia; pudendal neuralgia by pudendal nerve entrapment; pudendalgia","Curated_Disease_Description_Source__c":"GARD:0010713","Curated_Disease_Description__c":"Pudendal Neuralgia occurs when the pudendal nerve is injured, irritated, or compressed. Symptoms include burning pain (often unilateral), tingling, or numbness in any of the following areas: buttocks, genitals, or perineum (area between the buttocks and genitals). Symptoms are typically present when a person is sitting but often go away when the person is standing or lying down. The pain tends to increase as the day progresses. Additional symptoms include pain during sex and needing to urinate frequently and/or urgently. Damage to the pudendal nerve can result from surgical procedures, childbirth, trauma, spasms of the pelvic floor muscles, or tumors. Pudendal Neuralgia may also result from certain infections (such as herpes simplex infections) or certain activities (such as cycling and squatting exercises). There are no imaging studies that diagnose Pudendal Neuralgia; however, MRI and CT may help to exclude other causes of the pain.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"200,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:60039","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0018957","ORPHANET_ID__c":"ORPHA:60039","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Síndrome de atrapamiento del nervio pudendo","Spanish_Description_Source__c":"ORPHA:60039","Spanish_Description__c":"Es una neuropatía periférica adquirida poco frecuente caracterizada por un dolor neuropático crónico que afecta al territorio sensorial del nervio pudendo (del clítoris al ano o del pene al ano), agravado al sentarse. A menudo se asocia con una disfunción pélvica.","Spanish_Disease_Name__c":"síndrome de atrapamiento del nervio pudendo","Spanish_GARD_Synonym__c":"algia pudenda; neuralgia del pudendo; neuralgia pudenda por atrapamiento del nervio pudendo; neuropatía pudenda; pudendalgia; síndrome de alcock; síndrome de dolor neuropático pudendo","Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Pudendal Neuralgia occurs when the pudendal nerve is injured, irritated, or compressed. Symptoms include burning pain (often unilateral), tingling, or numbness in any of the following areas: buttocks, genitals, or perineum (area between the buttocks and genitals). Symptoms are typically present when a person is sitting but often go away when the person is standing or lying down. The pain tends to increase as the day progresses. Additional symptoms include pain during sex and needing to urinate frequently and/or urgently. Damage to the pudendal nerve can result from surgical procedures, childbirth, trauma, spasms of the pelvic floor muscles, or tumors. Pudendal Neuralgia may also result from certain infections (such as herpes simplex infections) or certain activities (such as cycling and squatting exercises). There are no imaging studies that diagnose Pudendal Neuralgia; however, MRI and CT may help to exclude other causes of the pain.","Curated_Disease_Description_Source__c":"GARD:0010713","GARD_Synonym__c":"alcock syndrome; neuralgia of pudendal nerve; pudendal algia; pudendal nerve entrapment syndrome; pudendal nerve neuralgia; pudendal neuralgia by pudendal nerve entrapment; pudendalgia","Name":"Pudendal neuralgia","Curated_USA_Estimate__c":"200,000","estimateUsa":"200,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Pudendal Neuralgia Association","Website__c":"https://www.pudendalassociation.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"},{"Tag_Name__c":"Peripheral Neuropathy","Tag_Category__c":"Account","curated_tag_name":"Peripheral neuropathy"},{"Tag_Name__c":"Neuromuscular medicine","Tag_Category__c":"Specialist","curated_tag_name":"Neuromuscular medicine"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:60039"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1997249","Source__c":"C1997249","Xref__c":"C1997249"},{"URL__c":"https://www.orpha.net/en/disease/detail/60039","Source__c":"C1997249; MONDO:0018957","Xref__c":"ORPHA:60039"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=372681","Source__c":"C1997249","Xref__c":"MEDGEN:372681"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C060545","Source__c":"C1997249; MONDO:0018957","Xref__c":"D060545"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=427972000","Source__c":"C1997249; MONDO:0018957","Xref__c":"427972000"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018957","Source__c":"GARD:0010713","Xref__c":"MONDO:0018957"}],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Pain in and around the anus or rectum (perianal region).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0500005","HPO_Synonym__c":"Anal pain; Anorectal pain; Proctalgia; Rectal pain","HPO_Name__c":"Anal pain","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"A multidimensional but common male sexual dysfunction that involves an alteration in any of the components of the erectile response, including organic, relational and psychological.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0100639","HPO_Synonym__c":"Abnormal erection; Erectile abnormalities","HPO_Name__c":"Erectile dysfunction","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Excluded (0%)","Feature__r":{"HPO_Description__c":"An adenoma carcinoma that originates in the anal canal.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0030439","HPO_Name__c":"Anal canal adenocarcinoma","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the scrotum.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0030155","HPO_Synonym__c":"Scrotal pain","HPO_Name__c":"Scrotal pain","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Painful or difficult urination.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0100518","HPO_Synonym__c":"Painful or difficult urination","HPO_Name__c":"Dysuria","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Recurrent or persistent genital pain associated with sexual intercourse.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0030016","HPO_Name__c":"Dyspareunia","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Pain (An unpleasant sensory and emotional experience) along the course of a nerve.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0033345","HPO_Name__c":"Neuralgia","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Pain perceived in the area of the pelvis, the lower part of the abdomen located between the hip bones.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0034267","HPO_Synonym__c":"Pain in the pelvis","HPO_Name__c":"Pelvic pain","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Increased frequency of urination.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0100515","HPO_Synonym__c":"Frequent urination","HPO_Name__c":"Pollakisuria","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Excluded (0%)","Feature__r":{"HPO_Description__c":"A tumor (abnormal growth of tissue) of the genitourinary system.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0007379","HPO_Synonym__c":"Genitourinary tract neoplasm; Genitourinary tract tumors; Neoplasm of the GU tract","HPO_Name__c":"Neoplasm of the genitourinary tract","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"A perception that an object located in the vagina.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0034806","HPO_Name__c":"Vaginal foreign body sensation","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Excluded (0%)","Feature__r":{"HPO_Description__c":"A tumor (abnormal growth of tissue) of the genital system.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0010787","HPO_Synonym__c":"Genital tumor","HPO_Name__c":"Genital neoplasm","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Pain due to a stimulus that does not normally provoke pain.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0012533","HPO_Name__c":"Allodynia","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Excluded (0%)","Feature__r":{"HPO_Description__c":"Pruritus is an itch or a sensation that makes a person want to scratch. This term refers to an abnormally increased disposition to experience pruritus.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0000989","HPO_Synonym__c":"Itching; Itchy skin; Skin itching","HPO_Name__c":"Pruritus","Feature_System__c":"Skin System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Excluded (0%)","Feature__r":{"HPO_Description__c":"An abnormality of the function of the electrical signals with which nerve cells communicate with each other or with muscles as measured by electrophysiological investigations.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001311","HPO_Synonym__c":"Neurophysiologic abnormalities; Neurophysiologic abnormality","HPO_Name__c":"Abnormal nervous system electrophysiology","Feature_System__c":"Nervous System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Excruciating burning pain in the rectal area that may be triggered by defecation.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0032150","HPO_Name__c":"Paroxysmal rectal pain","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Pain in the vulvar area","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0030943","HPO_Synonym__c":"Vulvar pain","HPO_Name__c":"Vulvodynia","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Excluded (0%)","Feature__r":{"HPO_Description__c":"An abnormality of the primary sensation that is mediated by peripheral nerves (pain, temperature, touch, vibration, joint position). The word hypoesthesia (or hypesthesia) refers to a reduction in cutaneous sensation to a specific type of testing.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0003474","HPO_Synonym__c":"Sensory impairment","HPO_Name__c":"Somatic sensory dysfunction","Feature_System__c":"Nervous System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:60039","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the buttock (round fleshy area at the lower rear area of a human trunk).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0034805","HPO_Name__c":"Buttock pain","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Disease Category":["Neurology"],"Specialist":["Neurology","Neuromuscular medicine"],"Account":["Peripheral Neuropathy"]},"synonyms":["alcock syndrome"," neuralgia of pudendal nerve"," pudendal algia"," pudendal nerve entrapment syndrome"," pudendal nerve neuralgia"," pudendal neuralgia by pudendal nerve entrapment"," pudendalgia"]}