{"Name":"Peritoneal multicystic mesothelioma","DiseaseID__c":"GARD:0010777","id":10777,"encodedName":"peritoneal-multicystic-mesothelioma","IsDeleted":false,"Disease_Name_Full__c":"Peritoneal multicystic mesothelioma","Xref_IDs__c":"716650003; C1334818; C6536; MEDGEN:233198; MONDO:0006363; ORPHA:168816","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0006363","Disease_Description__c":"A cystic mesothelioma that arises from the peritoneum and usually affects young to middle aged females. Grossly, it presents as a large multiloculated tumor mass, usually in the pelvic peritoneum. Histologically it is characterized by the presence of multiple cysts that are lined by one or more layers of mesothelial cells that do not show atypia. Patients usually present with abdominal or pelvic mass and pain. The clinical course is indolent. The tumor may recur, but transformation to diffuse malignant mesothelioma is rare.","GARD_Name__c":"Peritoneal multicystic mesothelioma","GARD_Synonym__c":"benign multicystic peritoneal mesothelioma; cystic mesothelioma of peritoneum; multicystic mesothelioma; multicystic mesothelioma of peritoneum; multicystic mesothelioma of the peritoneum; multilocular peritoneal inclusion cyst; peritoneal cystic mesothelioma","Curated_Disease_Description_Source__c":"GARD:0010777","Curated_Disease_Description__c":"Peritoneal cystic mesothelioma (BMPM) is a very rare benign cystic tumor arising from the peritoneal mesothelium (lining of the abdominal wall). It commonly occurs in young to middle-aged women who have a prior history of abdominal surgery, endometriosis, or pelvic inflammatory disease. The first symptoms usually include abdominal or pelvic pain, tenderness, and rarely, constipation and/or urinary hesitancy. Since it was first described in 1979, there have been approximately 130 cases described in the medical literature. Peritoneal cystic mesothelioma is not related to prior asbestos exposure. The specific cause is unknown.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:168816","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0006363","ORPHANET_ID__c":"ORPHA:168816","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Quiste de inclusión peritoneal","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"quiste de inclusión peritoneal","Spanish_GARD_Synonym__c":"mesotelioma multiquístico; mesotelioma peritoneal multiquístico benigno; mesotelioma peritoneal quístico; quiste de inclusión peritoneal multilocular","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Peritoneal cystic mesothelioma (BMPM) is a very rare benign cystic tumor arising from the peritoneal mesothelium (lining of the abdominal wall). It commonly occurs in young to middle-aged women who have a prior history of abdominal surgery, endometriosis, or pelvic inflammatory disease. The first symptoms usually include abdominal or pelvic pain, tenderness, and rarely, constipation and/or urinary hesitancy. Since it was first described in 1979, there have been approximately 130 cases described in the medical literature. Peritoneal cystic mesothelioma is not related to prior asbestos exposure. The specific cause is unknown.","Curated_Disease_Description_Source__c":"GARD:0010777","GARD_Synonym__c":"benign multicystic peritoneal mesothelioma; cystic mesothelioma of peritoneum; multicystic mesothelioma; multicystic mesothelioma of peritoneum; multicystic mesothelioma of the peritoneum; multilocular peritoneal inclusion cyst; peritoneal cystic mesothelioma","Name":"Peritoneal multicystic mesothelioma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Mesothelioma Guide","Website__c":"https://www.mesotheliomaguide.com/"},{"Account_Name__c":"Mesothelioma Applied Research Foundation","Website__c":"https://www.curemeso.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:168816"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C6536","Source__c":"C1334818; MONDO:0006363","Xref__c":"C6536"},{"URL__c":"https://www.orpha.net/en/disease/detail/168816","Source__c":"C1334818; MONDO:0006363; ORPHA:168816","Xref__c":"ORPHA:168816"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=716650003","Source__c":"C1334818; MONDO:0006363","Xref__c":"716650003"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=233198","Source__c":"C1334818","Xref__c":"MEDGEN:233198"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1334818","Source__c":"C1334818","Xref__c":"C1334818"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0006363","Source__c":"GARD:0010777","Xref__c":"MONDO:0006363"}],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Inflammation of the peritoneum.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002586","HPO_Synonym__c":"Inflammation of the peritoneum","HPO_Name__c":"Peritonitis","Feature_System__c":"Immune System; Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002664","HPO_Synonym__c":"Neoplasia; Oncological abnormality; Tumor; Tumour","HPO_Name__c":"Neoplasm","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Reduction of total body weight.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001824","HPO_Synonym__c":"Loss of weight","HPO_Name__c":"Weight loss","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Bleeding at irregular intervals.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0100608","HPO_Synonym__c":"Abnormal uterus bleeding; Intermenstrual bleeding; Menstrual spotting","HPO_Name__c":"Metrorrhagia","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Prolonged and excessive menses at regular intervals in excess of 80 mL or lasting longer than 7 days.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0000132","HPO_Synonym__c":"Abnormally heavy bleeding during menstruation; Abnormally heavy periods; Hypermenorrhea","HPO_Name__c":"Menorrhagia","Feature_System__c":"Blood and Blood-Forming Tissue","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002027","HPO_Synonym__c":"Abdominal pain; Pain in stomach; Stomach pain","HPO_Name__c":"Abdominal pain","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Distention of the abdomen.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0003270","HPO_Synonym__c":"Abdominal bloating; Abdominal distension; Abdominal swelling; Belly bloating; Bloating; Distended abdomen","HPO_Name__c":"Abdominal distention","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Infrequent or difficult evacuation of feces.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002019","HPO_Synonym__c":"Constipation; Costiveness; Dyschezia","HPO_Name__c":"Constipation","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168816","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Recurrent or persistent genital pain associated with sexual intercourse.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0030016","HPO_Name__c":"Dyspareunia","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Cancer - Oncologist"],"Disease Category":["Cancer"]},"synonyms":["benign multicystic peritoneal mesothelioma"," cystic mesothelioma of peritoneum"," multicystic mesothelioma"," multicystic mesothelioma of peritoneum"," multicystic mesothelioma of the peritoneum"," multilocular peritoneal inclusion cyst"," peritoneal cystic mesothelioma"]}