{"Name":"Medial condensing osteitis of the clavicle","DiseaseID__c":"GARD:0010910","id":10910,"encodedName":"medial-condensing-osteitis-of-the-clavicle","IsDeleted":false,"Disease_Name_Full__c":"Medial condensing osteitis of the clavicle","Xref_IDs__c":"C5396729; MEDGEN:1710994; MONDO:0018929; ORPHA:57196","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":3,"Description_Source__c":"ORPHA:57196","Disease_Description__c":"A rare bone disease characterized by benign, usually unilateral, sclerosis of the inferomedial third of the clavicle. Patients present with localized swelling and persistent pain. Typical radiographic findings are expansion of the medial end of the clavicle with increased radio-density and signs of bone remodeling.","GARD_Name__c":"Medial condensing osteitis of the clavicle","GARD_Synonym__c":"condensing osteitis of the clavicle; condensing osteitis of the medial clavicle; medial condensing osteitis of clavicle; osteitis condensans of medial clavicle; osteitis condensans of the clavicle","Curated_Disease_Description_Source__c":"ORPHA:57196","Curated_Disease_Description__c":"A rare bone disease characterized by benign, usually unilateral, sclerosis of the inferomedial third of the clavicle. Patients present with localized swelling and persistent pain. Typical radiographic findings are expansion of the medial end of the clavicle with increased radio-density and signs of bone remodeling.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"from Childhood to Adulthood","SourceID__c":"ORPHA:57196","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0018929","ORPHANET_ID__c":"ORPHA:57196","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Osteítis condensante medial de la clavícula","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"osteítis condensante medial de la clavícula","Spanish_GARD_Synonym__c":"osteítis condensante de la clavícula","Category_Linearization__c":"ORPHA:93419","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare bone disease characterized by benign, usually unilateral, sclerosis of the inferomedial third of the clavicle. Patients present with localized swelling and persistent pain. Typical radiographic findings are expansion of the medial end of the clavicle with increased radio-density and signs of bone remodeling.","Curated_Disease_Description_Source__c":"ORPHA:57196","GARD_Synonym__c":"condensing osteitis of the clavicle; condensing osteitis of the medial clavicle; medial condensing osteitis of clavicle; osteitis condensans of medial clavicle; osteitis condensans of the clavicle","Name":"Medial condensing osteitis of the clavicle","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Rheumatology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Orthopedics","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:57196"},{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:57196"},{"Age_At_Onset__c":"Adolescent","Provided_By__c":"ORPHA:57196"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1710994","Source__c":"C5396729","Xref__c":"MEDGEN:1710994"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5396729","Source__c":"C5396729","Xref__c":"C5396729"},{"URL__c":"https://www.orpha.net/en/disease/detail/57196","Source__c":"C5396729; MONDO:0018929; ORPHA:57196","Xref__c":"ORPHA:57196"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=870320009","Source__c":"C5396729","Xref__c":"870320009"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018929","Source__c":"GARD:0010910","Xref__c":"MONDO:0018929"}],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:57196","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Any abnormality of the clavicles (collar bones).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0000889","HPO_Synonym__c":"Abnormal clavicles; Abnormal collarbone; Abnormality of the clavicle","HPO_Name__c":"Abnormal clavicle morphology","Feature_System__c":"Musculoskeletal System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:57196","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) localized to the shoulder.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0030834","HPO_Synonym__c":"Shoulder pain","HPO_Name__c":"Shoulder pain","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:57196","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"A limitation of the range of movement of the shoulder joint.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0006467","HPO_Synonym__c":"Limited shoulder movement","HPO_Name__c":"Limited shoulder movement","Feature_System__c":"Musculoskeletal System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:57196","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"An abnormal elevation of the C-reactive protein level in the blood circulation.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0011227","HPO_Synonym__c":"Elevated C-reactive protein level","HPO_Name__c":"Elevated circulating C-reactive protein concentration","HPO_Feature_Type__c":"Lab"}},{"Provided_By__c":"ORPHA:57196","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Patchy (irregular) reduction in bone density. This can take on many forms depending on severity and distribution as can be seen on x-rays.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0010657","HPO_Name__c":"Patchy reduction of bone mineral density","Feature_System__c":"Musculoskeletal System","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Rheumatology","Orthopedics","Pediatrics"]},"synonyms":["condensing osteitis of the clavicle"," condensing osteitis of the medial clavicle"," medial condensing osteitis of clavicle"," osteitis condensans of medial clavicle"," osteitis condensans of the clavicle"]}