{"Name":"Dirofilariasis","DiseaseID__c":"GARD:0011908","id":11908,"encodedName":"dirofilariasis","IsDeleted":false,"Disease_Name_Full__c":"Dirofilariasis","Xref_IDs__c":"73328005; C0012602; D004184; DOID:1082; MEDGEN:4344; MONDO:0015636; ORPHA:166291","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0015636","Disease_Description__c":"Infection with nematodes of the genus dirofilaria, usually in animals, especially dogs, but occasionally in humans.","GARD_Name__c":"Dirofilariasis","GARD_Synonym__c":"dirofilaria caused disease or disorder; dirofilaria disease or disorder; dirofilaria infectious disease; dirofilariosis; infection by dirofilaria; infection caused by dirofilaria","Curated_Disease_Description_Source__c":"GARD:0011908","Curated_Disease_Description__c":"Dirofilariasis refers to infections caused by Dirofilaria roundworms. Although the natural hosts of these roundworms are dogs, wild canids (such as wolves and foxes) and raccoons, humans can be infected with Dirofilaria larvae through mosquito bites. Signs and symptoms of Dirofilariasis generally include nodules under the skin or lung granulomas (small nodules formed by an inflammatory reaction) which may be asymptomatic. Some people with Dirofilariasis of the lungs may also experience cough, chest pain, fever, wheezing, chills, and pleural effusion (excess fluid between the tissues that line the lungs and the chest cavity).","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:166291","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0015636","ORPHANET_ID__c":"ORPHA:166291","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Dirofilariasis","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"dirofilariasis","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Dirofilariasis refers to infections caused by Dirofilaria roundworms. Although the natural hosts of these roundworms are dogs, wild canids (such as wolves and foxes) and raccoons, humans can be infected with Dirofilaria larvae through mosquito bites. Signs and symptoms of Dirofilariasis generally include nodules under the skin or lung granulomas (small nodules formed by an inflammatory reaction) which may be asymptomatic. Some people with Dirofilariasis of the lungs may also experience cough, chest pain, fever, wheezing, chills, and pleural effusion (excess fluid between the tissues that line the lungs and the chest cavity).","Curated_Disease_Description_Source__c":"GARD:0011908","GARD_Synonym__c":"dirofilaria caused disease or disorder; dirofilaria disease or disorder; dirofilaria infectious disease; dirofilariosis; infection by dirofilaria; infection caused by dirofilaria","Name":"Dirofilariasis","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Parasitic Disease","Tag_Category__c":"Cause","curated_tag_name":"Parasitic Infectious Diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:166291"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=4344","Source__c":"C0012602","Xref__c":"MEDGEN:4344"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C004184","Source__c":"C0012602; MONDO:0015636","Xref__c":"D004184"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=73328005","Source__c":"C0012602; MONDO:0015636","Xref__c":"73328005"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0012602","Source__c":"C0012602","Xref__c":"C0012602"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A1082","Source__c":"MONDO:0015636","Xref__c":"DOID:1082"},{"URL__c":"https://www.orpha.net/en/disease/detail/166291","Source__c":"C0012602; MONDO:0015636; ORPHA:166291","Xref__c":"ORPHA:166291"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0015636","Source__c":"GARD:0011908","Xref__c":"MONDO:0015636"},{"URL__c":"https://www.cdc.gov/dirofilariasis/about/index.html"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Parasitic Disease"]},"synonyms":["dirofilaria caused disease or disorder"," dirofilaria disease or disorder"," dirofilaria infectious disease"," dirofilariosis"," infection by dirofilaria"," infection caused by dirofilaria"]}