{"Name":"Autoimmune encephalitis","DiseaseID__c":"GARD:0011979","id":11979,"encodedName":"autoimmune-encephalitis","IsDeleted":false,"Disease_Name_Full__c":"Autoimmune encephalitis","Xref_IDs__c":"95643007; C122414; C5671289; MEDGEN:1804547; MONDO:0020640; ORPHA:622014","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0020640","Disease_Description__c":"Inflammation of the brain secondary to an immune response triggered by the body itself.","GARD_Name__c":"Autoimmune encephalitis","GARD_Synonym__c":"autoimmune encephalopathy","Curated_Disease_Description_Source__c":"GARD:0011979","Curated_Disease_Description__c":"Autoimmune encephalitis refers to a group of conditions that occur when the body's immune system mistakenly attacks healthy brain cells, leading to inflammation of the brain. People with Autoimmune encephalitis may have various neurologic and/or psychiatric symptoms. Neurologic symptoms may include impaired memory and cognition, abnormal movements, seizures, and/or problems with balance, speech, or vision. Psychiatric symptoms may include psychosis, aggression, inappropriate sexual behaviors, panic attacks, compulsive behaviors, euphoria or fear. Symptoms may fluctuate, but often progress over days to a few weeks. Symptoms can progress to loss of consciousness or even coma. Autoimmune encephalitis may be associated with antibodies to proteins on the surface of nerve cells, or within nerve cells. Some of these proteins are involved in passing signals between nerve cells. In some cases it occurs in association with cancer (a paraneoplastic syndrome). Research regarding why specific antibodies attack the body's healthy cells is ongoing. Autoimmune encephalitis generally occurs sporadically, in people with no family history of the condition.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:622014","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0020640","ORPHANET_ID__c":"ORPHA:622014","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Encefalitis autoinmune","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"encefalitis autoinmune","Spanish_GARD_Synonym__c":"ea; eai","Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Autoimmune encephalitis refers to a group of conditions that occur when the body's immune system mistakenly attacks healthy brain cells, leading to inflammation of the brain. People with Autoimmune encephalitis may have various neurologic and/or psychiatric symptoms. Neurologic symptoms may include impaired memory and cognition, abnormal movements, seizures, and/or problems with balance, speech, or vision. Psychiatric symptoms may include psychosis, aggression, inappropriate sexual behaviors, panic attacks, compulsive behaviors, euphoria or fear. Symptoms may fluctuate, but often progress over days to a few weeks. Symptoms can progress to loss of consciousness or even coma. Autoimmune encephalitis may be associated with antibodies to proteins on the surface of nerve cells, or within nerve cells. Some of these proteins are involved in passing signals between nerve cells. In some cases it occurs in association with cancer (a paraneoplastic syndrome). Research regarding why specific antibodies attack the body's healthy cells is ongoing. Autoimmune encephalitis generally occurs sporadically, in people with no family history of the condition.","Curated_Disease_Description_Source__c":"GARD:0011979","GARD_Synonym__c":"autoimmune encephalopathy","Name":"Autoimmune encephalitis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Global Autoimmune Institute","Website__c":"https://www.autoimmuneinstitute.org/"},{"Account_Name__c":"Encephalitis411","Website__c":"https://encephalitis411.org/"},{"Account_Name__c":"Autoimmune Registry","Website__c":"https://www.autoimmuneregistry.org/"},{"Account_Name__c":"Encephalitis Society","Website__c":"https://www.encephalitis.info/"},{"Account_Name__c":"Autoimmune Association","Website__c":"https://autoimmune.org/"},{"Account_Name__c":"Hashimoto's Encephalopathy SREAT Alliance","Website__c":"https://www.hesaonline.info/"},{"Account_Name__c":"Autoimmune Encephalitis Alliance","Website__c":"https://aealliance.org/"},{"Account_Name__c":"International Autoimmune Encephalitis Society","Website__c":"https://autoimmune-encephalitis.org/"},{"Account_Name__c":"Neuroimmune Foundation","Website__c":"https://www.neuroimmune.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C122414","Source__c":"C5671289; MONDO:0020640","Xref__c":"C122414"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1804547","Source__c":"C5671289","Xref__c":"MEDGEN:1804547"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5671289","Source__c":"C5671289","Xref__c":"C5671289"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=95643007","Source__c":"C5671289; MONDO:0020640","Xref__c":"95643007"},{"URL__c":"https://www.orpha.net/en/disease/detail/622014","Source__c":"MONDO:0020640","Xref__c":"ORPHA:622014"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0020640","Source__c":"GARD:0011979","Xref__c":"MONDO:0020640"}],"tags":{"Disease Category":["Neurology"],"Specialist":["Neurology"]},"synonyms":["autoimmune encephalopathy"]}