{"Name":"Primary melanoma of the central nervous system","DiseaseID__c":"GARD:0012016","id":12016,"encodedName":"primary-melanoma-of-the-central-nervous-system","IsDeleted":false,"Disease_Name_Full__c":"Primary melanoma of the central nervous system","Xref_IDs__c":"C0349626; C5317; MEDGEN:578849; MONDO:0016747; ORPHA:252050","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0016747","Disease_Description__c":"A melanoma that affects the central nervous system. It is characterized by pleomorphism, melanin pigmentation, a high mitotic rate, necrosis, and hemorrhage. It is a highly aggressive and radioresistant tumor. The prognosis is usually poor.","GARD_Name__c":"Primary melanoma of the central nervous system","GARD_Synonym__c":"central nervous system melanoma; central nervous system melanoma (disease); cns melanoma; malignant melanoma of meninges; melanoma (disease) of central nervous system; melanoma of central nervous system; melanoma of cns; melanoma of the central nervous system; melanoma of the cns; meningeal melanoma; primary melanoma of the cns","Curated_Disease_Description_Source__c":"MONDO:0016747","Curated_Disease_Description__c":"A melanoma that affects the central nervous system. It is characterized by pleomorphism, melanin pigmentation, a high mitotic rate, necrosis, and hemorrhage. It is a highly aggressive and radioresistant tumor. The prognosis is usually poor.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:252050","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0016747","ORPHANET_ID__c":"ORPHA:252050","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Melanoma primario del sistema nervioso central","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"melanoma primario del sistema nervioso central","Spanish_GARD_Synonym__c":"melanoma maligno de meníngeo; melanoma primario del snc","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A melanoma that affects the central nervous system. It is characterized by pleomorphism, melanin pigmentation, a high mitotic rate, necrosis, and hemorrhage. It is a highly aggressive and radioresistant tumor. The prognosis is usually poor.","Curated_Disease_Description_Source__c":"MONDO:0016747","GARD_Synonym__c":"central nervous system melanoma; central nervous system melanoma (disease); cns melanoma; malignant melanoma of meninges; melanoma (disease) of central nervous system; melanoma of central nervous system; melanoma of cns; melanoma of the central nervous system; melanoma of the cns; meningeal melanoma; primary melanoma of the cns","Name":"Primary melanoma of the central nervous system","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Brain Tumor Association","Website__c":"https://www.abta.org/"},{"Account_Name__c":"National Brain Tumor Society","Website__c":"https://braintumor.org/"},{"Account_Name__c":"Melanoma Research Alliance","Website__c":"https://www.curemelanoma.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:252050"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=578849","Source__c":"C0349626","Xref__c":"MEDGEN:578849"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0349626","Source__c":"C0349626","Xref__c":"C0349626"},{"URL__c":"https://www.orpha.net/en/disease/detail/252050","Source__c":"C0349626; MONDO:0016747; ORPHA:252050","Xref__c":"ORPHA:252050"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=277530005","Source__c":"C0349626","Xref__c":"277530005"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0016747","Source__c":"GARD:0012016","Xref__c":"MONDO:0016747"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=726420002","Source__c":"C0349626","Xref__c":"726420002"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C5317","Source__c":"C0349626","Xref__c":"C5317"}],"tags":{"Specialist":["Cancer - Oncologist","Neurology"],"Disease Category":["Cancer","Neurology"]},"synonyms":["central nervous system melanoma"," central nervous system melanoma (disease)"," cns melanoma"," malignant melanoma of meninges"," melanoma (disease) of central nervous system"," melanoma of central nervous system"," melanoma of cns"," melanoma of the central nervous system"," melanoma of the cns"," meningeal melanoma"," primary melanoma of the cns"]}