{"Name":"Situs inversus with levocardia","DiseaseID__c":"GARD:0012032","id":12032,"encodedName":"situs-inversus-with-levocardia","IsDeleted":false,"Disease_Name_Full__c":"Situs inversus with levocardia","Xref_IDs__c":"205769006; C0023569; C111647; D007979; HP:0031592; MEDGEN:7331; MONDO:0019862; ORPHA:95854; Q24.1","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0019862","Disease_Description__c":"A condition where the heart is in the correct anatomic position but some or all of the other thoracoabdominal viscera are in the opposite lateral orientation.","GARD_Name__c":"Situs inversus with levocardia","GARD_Synonym__c":"isolated levocardia; levocardia; levocardia with situs inversus; levocardia-situs inversus","Curated_Disease_Description_Source__c":"GARD:0012032","Curated_Disease_Description__c":"Isolated levocardia is a type of situs inversus where the heart is located in the normal position, but there is a mirror-image reversal of other internal organs. Isolated levocardia may occur alone or with heart defects, heart rhythm abnormalities (sick sinus syndrome or atrioventricular node disorder), spleen defects (absent, underdeveloped, or extra spleen), and intestinal malrotation. The cause of Isolated levocardia is not known. It is not usually associated with chromosome abnormalities.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:95854","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0019862","ORPHANET_ID__c":"ORPHA:95854","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Levocardia","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"levocardia","Spanish_GARD_Synonym__c":"levocardia aislada; levocardia con situs inversus","Category_Linearization__c":"ORPHA:93890","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Isolated levocardia is a type of situs inversus where the heart is located in the normal position, but there is a mirror-image reversal of other internal organs. Isolated levocardia may occur alone or with heart defects, heart rhythm abnormalities (sick sinus syndrome or atrioventricular node disorder), spleen defects (absent, underdeveloped, or extra spleen), and intestinal malrotation. The cause of Isolated levocardia is not known. It is not usually associated with chromosome abnormalities.","Curated_Disease_Description_Source__c":"GARD:0012032","GARD_Synonym__c":"isolated levocardia; levocardia; levocardia with situs inversus; levocardia-situs inversus","Name":"Situs inversus with levocardia","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Heart Association","Website__c":"https://www.heart.org"},{"Account_Name__c":"Mended Hearts","Website__c":"https://mendedhearts.org/"},{"Account_Name__c":"The Children's Heart Foundation","Website__c":"https://www.childrensheartfoundation.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cardiology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Congenital Abnormality","Tag_Category__c":"Disease Category","category_description":"Birth defects are structural changes present at birth that can affect almost any part of the body, including how the body looks, works, or both.","curated_tag_name":"Birth defects"},{"Tag_Name__c":"Congenital Heart Disease","Tag_Category__c":"Specialist","curated_tag_name":"Congenital heart disease"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C007979","Source__c":"C0023569; MONDO:0019862","Xref__c":"D007979"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/Q24.1","Source__c":"MONDO:0019862","Xref__c":"Q24.1"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C111647","Source__c":"C0023569; MONDO:0019862","Xref__c":"C111647"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0023569","Source__c":"C0023569","Xref__c":"C0023569"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=205769006","Source__c":"C0023569; MONDO:0019862","Xref__c":"205769006"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=7331","Source__c":"C0023569","Xref__c":"MEDGEN:7331"},{"URL__c":"https://www.orpha.net/en/disease/detail/95854","Source__c":"C0023569; MONDO:0019862; ORPHA:95854","Xref__c":"ORPHA:95854"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0031592","Source__c":"C0023569","Xref__c":"HP:0031592"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019862","Source__c":"GARD:0012032","Xref__c":"MONDO:0019862"}],"tags":{"Specialist":["Cardiology","Congenital Heart Disease"],"Disease Category":["Congenital Abnormality"]},"synonyms":["isolated levocardia"," levocardia"," levocardia with situs inversus"," levocardia-situs inversus"]}