{"Name":"Melanoma associated retinopathy","DiseaseID__c":"GARD:0012041","id":12041,"encodedName":"melanoma-associated-retinopathy","IsDeleted":false,"Disease_Name_Full__c":"Melanoma associated retinopathy","Xref_IDs__c":"312941005; C0730308; MEDGEN:452708; MONDO:0023868","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0023868","Disease_Description__c":"Melanoma-associated retinopathy (MAR) is a rare autoimmune condition that occurs in some people with melanoma (a type of skin cancer) and can affect the vision.","GARD_Name__c":"Melanoma associated retinopathy","GARD_Synonym__c":"melanoma-associated retinopathy","Curated_Disease_Description_Source__c":"GARD:0012041","Curated_Disease_Description__c":"Melanoma-associated retinopathy (MAR) is a rare autoimmune condition that occurs in some people with melanoma (a type of skin cancer) and can affect the vision. Signs and symptoms of MAR may include night blindness; photopsia (presence of perceived flashes of light); and progressive, painless vision loss. MAR occurs when the body's immune system, in response to melanoma, mistakenly attacks the cells of the retina; however, it is poorly understood why this autoimmune response occurs in some people but not others.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0023868","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Melanoma-associated retinopathy (MAR) is a rare autoimmune condition that occurs in some people with melanoma (a type of skin cancer) and can affect the vision. Signs and symptoms of MAR may include night blindness; photopsia (presence of perceived flashes of light); and progressive, painless vision loss. MAR occurs when the body's immune system, in response to melanoma, mistakenly attacks the cells of the retina; however, it is poorly understood why this autoimmune response occurs in some people but not others.","Curated_Disease_Description_Source__c":"GARD:0012041","GARD_Synonym__c":"melanoma-associated retinopathy","Name":"Melanoma associated retinopathy","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Melanoma Research Alliance","Website__c":"https://www.curemelanoma.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Retinal","Tag_Category__c":"Account;Specialist","curated_tag_name":"Retinal disorders"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=312941005","Source__c":"C0730308; MONDO:0023868","Xref__c":"312941005"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=452708","Source__c":"C0730308","Xref__c":"MEDGEN:452708"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0730308","Source__c":"C0730308","Xref__c":"C0730308"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0023868","Source__c":"GARD:0012041","Xref__c":"MONDO:0023868"}],"tags":{"Account":["Retinal"],"Specialist":["Retinal"]},"synonyms":["melanoma-associated retinopathy"]}