{"Name":"Plasmablastic lymphoma","DiseaseID__c":"GARD:0012125","id":12125,"encodedName":"plasmablastic-lymphoma","IsDeleted":false,"Disease_Name_Full__c":"Plasmablastic lymphoma","Xref_IDs__c":"423022274; 450909005; 724648008; C3472614; C7224; D000069293; DOID:0080779; MEDGEN:483338; MONDO:0017347; ORPHA:289666","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0017347","Disease_Description__c":"An aggressive diffuse large B-cell lymphoma frequently arising in the setting of HIV infection and characterized by the presence of large neoplastic cells resembling B-immunoblasts which have the immunophenotypic profile of plasma cells. Sites of involvement include the oral cavity, sinonasal cavity, skin, soft tissues, gastrointestinal tract, and bone.","GARD_Name__c":"Plasmablastic lymphoma","GARD_Synonym__c":"pbl","Curated_Disease_Description_Source__c":"GARD:0012125","Curated_Disease_Description__c":"Plasmablastic lymphoma is an aggressive form of non-Hodgkin lymphoma. Although the condition most commonly occurs in the oral cavity, it can be diagnosed in many other parts of the body such as the gastrointestinal tract, lymph nodes, and skin. The exact underlying cause of Plasmablastic lymphoma is poorly understood; however, it is often associated with suppression of the immune system (i.e. HIV infection, immunosuppressive therapy).","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:289666","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0017347","ORPHANET_ID__c":"ORPHA:289666","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Linfoma plasmablástico","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"linfoma plasmablástico","Spanish_GARD_Synonym__c":"pbl","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Plasmablastic lymphoma is an aggressive form of non-Hodgkin lymphoma. Although the condition most commonly occurs in the oral cavity, it can be diagnosed in many other parts of the body such as the gastrointestinal tract, lymph nodes, and skin. The exact underlying cause of Plasmablastic lymphoma is poorly understood; however, it is often associated with suppression of the immune system (i.e. HIV infection, immunosuppressive therapy).","Curated_Disease_Description_Source__c":"GARD:0012125","GARD_Synonym__c":"pbl","Name":"Plasmablastic lymphoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"The Oral Cancer Foundation","Website__c":"https://oralcancerfoundation.org/"},{"Account_Name__c":"Blood Cancer United","Website__c":"https://bloodcancerunited.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Hematology","Tag_Category__c":"Disease Category;Specialist","category_description":"Blood diseases affect the blood or blood-forming organs, including red blood cells, white blood cells, platelets, plasma, and bone marrow.","curated_tag_name":"Blood diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=724648008","Source__c":"C3472614; MONDO:0017347","Xref__c":"724648008"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0080779","Source__c":"MONDO:0017347","Xref__c":"DOID:0080779"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C000069293","Source__c":"C3472614; MONDO:0017347","Xref__c":"D000069293"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=483338","Source__c":"C3472614","Xref__c":"MEDGEN:483338"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C3472614","Source__c":"C3472614","Xref__c":"C3472614"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C7224","Source__c":"C3472614; MONDO:0017347","Xref__c":"C7224"},{"URL__c":"https://www.orpha.net/en/disease/detail/289666","Source__c":"C3472614; MONDO:0017347; ORPHA:289666","Xref__c":"ORPHA:289666"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=450909005","Source__c":"C3472614","Xref__c":"450909005"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0017347","Source__c":"GARD:0012125","Xref__c":"MONDO:0017347"},{"URL__c":"https://secure.ssa.gov/apps10/poms.nsf/lnx/0423022274","Xref__c":"423022274"}],"tags":{"Specialist":["Cancer - Oncologist","Hematology"],"Disease Category":["Cancer","Hematology"]},"synonyms":["pbl"]}