{"Name":"Cor triatriatum sinister","DiseaseID__c":"GARD:0012484","id":12484,"encodedName":"cor-triatriatum-sinister","IsDeleted":false,"Disease_Name_Full__c":"Cor triatriatum sinister","Xref_IDs__c":"253353007; C0344712; HP:0031134; MEDGEN:576445; MONDO:0020430; ORPHA:99099","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0020430","Disease_Description__c":"Cor triatriatum sinister (CTS) results when the left atrium is divided into two compartments by a membrane. The membrane can vary in size and shape and may have one or more openings. Severe cases of cor triatriatum sinister usually present in infancy and are often associated with other heart defects. In less severe cases, the diagnosis may not be made until later in life. The specific symptoms depend on the degree to which the membrane obstructs the flow of blood and whether or not there are additional heart defects. Symptoms may range from mild shortness of breath during exercise to signs of heart failure and lung congestion. Some people with CTS may not have symptoms. Treatment varies according to the severity of the symptoms. For symptomatic patients, surgery is generally consideredthe definitive course of therapy.","GARD_Name__c":"Cor triatriatum sinister","GARD_Synonym__c":"divided left atrium","Curated_Disease_Description_Source__c":"GARD:0012484","Curated_Disease_Description__c":"Cor triatriatum sinister (CTS) results when the left atrium is divided into two compartments by a membrane. The membrane can vary in size and shape and may have one or more openings. Severe cases of Cor triatriatum sinister usually present in infancy and are often associated with other heart defects. In less severe cases, the diagnosis may not be made until later in life. The specific symptoms depend on the degree to which the membrane obstructs the flow of blood and whether or not there are additional heart defects. Symptoms may range from mild shortness of breath during exercise to signs of heart failure and lung congestion. Some people with CTS may not have symptoms.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:99099","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0020430","ORPHANET_ID__c":"ORPHA:99099","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Cor triatriatum sinister","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"cor triatriatum sinister","Spanish_GARD_Synonym__c":"aurícula izquierda dividida; cor triatriatum sinistrum","Category_Linearization__c":"ORPHA:93890","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Cor triatriatum sinister (CTS) results when the left atrium is divided into two compartments by a membrane. The membrane can vary in size and shape and may have one or more openings. Severe cases of Cor triatriatum sinister usually present in infancy and are often associated with other heart defects. In less severe cases, the diagnosis may not be made until later in life. The specific symptoms depend on the degree to which the membrane obstructs the flow of blood and whether or not there are additional heart defects. Symptoms may range from mild shortness of breath during exercise to signs of heart failure and lung congestion. Some people with CTS may not have symptoms.","Curated_Disease_Description_Source__c":"GARD:0012484","GARD_Synonym__c":"divided left atrium","Name":"Cor triatriatum sinister","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Heart Association","Website__c":"https://www.heart.org"},{"Account_Name__c":"The Children's Heart Foundation","Website__c":"https://www.childrensheartfoundation.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cardiology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Congenital Abnormality","Tag_Category__c":"Disease Category","category_description":"Birth defects are structural changes present at birth that can affect almost any part of the body, including how the body looks, works, or both.","curated_tag_name":"Birth defects"},{"Tag_Name__c":"Congenital Heart Disease","Tag_Category__c":"Specialist","curated_tag_name":"Congenital heart disease"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=253353007","Source__c":"C0344712; MONDO:0020430","Xref__c":"253353007"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0344712","Source__c":"C0344712","Xref__c":"C0344712"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=576445","Source__c":"C0344712","Xref__c":"MEDGEN:576445"},{"URL__c":"https://www.orpha.net/en/disease/detail/99099","Source__c":"MONDO:0020430","Xref__c":"ORPHA:99099"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0020430","Source__c":"GARD:0012484","Xref__c":"MONDO:0020430"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0031134","Source__c":"C0344712","Xref__c":"HP:0031134"}],"tags":{"Specialist":["Cardiology","Congenital Heart Disease"],"Disease Category":["Congenital Abnormality"]},"synonyms":["divided left atrium"]}