{"Name":"Painful legs and moving toes syndrome","DiseaseID__c":"GARD:0012706","id":12706,"encodedName":"painful-legs-and-moving-toes-syndrome","IsDeleted":false,"Disease_Name_Full__c":"Painful legs and moving toes syndrome","Xref_IDs__c":"C5680388; MEDGEN:1842291; MONDO:0850049; ORPHA:617440","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":1,"Description_Source__c":"GARD:0012706","Disease_Description__c":"Painful legs and moving toes (PLMT) syndrome is an adult-onset, rare disorder characterized by pain in the feet or legs and twisting movements of one or more toes. The patients usually seek medical attention because of the pain. The syndrome may be unilateral or bilateral. Identical toe movements may occur without pain, referred to as: \"painless legs-moving toes,\" and a similar condition affects the upper limbs: \"painful arms-moving fingers.\" The cause of PLMT and its variants is not known but most reports suggest an association with a peripheral lesion, usually at the level of the root or nerve, though in many cases no cause is found.","GARD_Name__c":"Painful legs and moving toes syndrome","GARD_Synonym__c":"plmt syndrome","Curated_Disease_Description_Source__c":"PlainLanguagePilotV1-Sep23","Curated_Disease_Description__c":"A rare neurologic (adult-onset) movement disorder characterized by persistent pain (unilateral or bilateral) in the feet or legs (most commonly the hemi-lower limbs) and persistant twisting, non-rhythmic, involuntary movements of one or more toes. Chronic 'deep aching pulling pain' includes tingling, numbness, aching, dullness, cramp, shooting, sharp, burning, and prickling.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:617440","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0850049","ORPHANET_ID__c":"ORPHA:617440","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Síndrome de piernas dolorosas y dedos de los pies en movimiento","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"síndrome de piernas dolorosas y dedos de los pies en movimiento","Spanish_GARD_Synonym__c":"síndrome plmt","Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare neurologic (adult-onset) movement disorder characterized by persistent pain (unilateral or bilateral) in the feet or legs (most commonly the hemi-lower limbs) and persistant twisting, non-rhythmic, involuntary movements of one or more toes. Chronic 'deep aching pulling pain' includes tingling, numbness, aching, dullness, cramp, shooting, sharp, burning, and prickling.","Curated_Disease_Description_Source__c":"PlainLanguagePilotV1-Sep23","GARD_Synonym__c":"plmt syndrome","Name":"Painful legs and moving toes syndrome","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"International Parkinson and Movement Disorder Society","Website__c":"https://www.movementdisorders.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:617440"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/617440","Source__c":"C5680388; MONDO:0850049; ORPHA:617440","Xref__c":"ORPHA:617440"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5680388","Source__c":"C5680388","Xref__c":"C5680388"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1842291","Source__c":"C5680388","Xref__c":"MEDGEN:1842291"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0850049","Source__c":"GARD:0012706","Xref__c":"MONDO:0850049"}],"tags":{"Disease Category":["Neurology"],"Specialist":["Neurology"]},"synonyms":["plmt syndrome"]}