{"Name":"Staphylococcal scalded skin syndrome","DiseaseID__c":"GARD:0013158","id":13158,"encodedName":"staphylococcal-scalded-skin-syndrome","IsDeleted":false,"Disease_Name_Full__c":"Staphylococcal scalded skin syndrome","Xref_IDs__c":"200946001; 277475006; C0038165; C85077; D013206; DOID:9063; L00; MEDGEN:52484; MONDO:0018181; ORPHA:36236","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0018181","Disease_Description__c":"A blistering skin disorder caused by exfoliative toxins produced by Staphylococcus aureus infection. The toxins cause the formation of bullae and diffuse skin desquamation. The lesions may be localized or generalized, far away from the initial site of infection.","GARD_Name__c":"Staphylococcal scalded skin syndrome","GARD_Synonym__c":"dermatitis exfoliativa neonatorum; generalised exfoliative disease; generalized exfoliative disease; pemphigus neonatorum; ritter disease; ritter's disease; scalded skin syndrome; ssss; ssss - staphylococcal scalded skin syndrome; toxic epidermal necrolysis, subcorneal type","Curated_Disease_Description_Source__c":"ORPHA:36236","Curated_Disease_Description__c":"A rare staphylococcal toxemia caused by epidermolytic toxins of <i>Staphylococcus aureus</i> and characterized by the appearance of widespread erythematous patches, on which large blisters develop. Upon rupture of these blisters, the skin appears reddish and scalded. The lesions typically begin in the face and rapidly expand to other parts of the body. The disease may be complicated by pneumonia and sepsis. It most commonly affects newborns and infants.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:36236","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0018181","ORPHANET_ID__c":"ORPHA:36236","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Síndrome de la piel escaldada por estafilococos","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"síndrome de la piel escaldada por estafilococos","Spanish_GARD_Synonym__c":"enfermedad exfoliativa generalizada; ssss","Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare staphylococcal toxemia caused by epidermolytic toxins of <i>Staphylococcus aureus</i> and characterized by the appearance of widespread erythematous patches, on which large blisters develop. Upon rupture of these blisters, the skin appears reddish and scalded. The lesions typically begin in the face and rapidly expand to other parts of the body. The disease may be complicated by pneumonia and sepsis. It most commonly affects newborns and infants.","Curated_Disease_Description_Source__c":"ORPHA:36236","GARD_Synonym__c":"dermatitis exfoliativa neonatorum; generalised exfoliative disease; generalized exfoliative disease; pemphigus neonatorum; ritter disease; ritter's disease; scalded skin syndrome; ssss; ssss - staphylococcal scalded skin syndrome; toxic epidermal necrolysis, subcorneal type","Name":"Staphylococcal scalded skin syndrome","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Bacterial Infectious Disease","Tag_Category__c":"Cause","curated_tag_name":"Bacterial Infectious Disease"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:36236"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0038165","Source__c":"C0038165","Xref__c":"C0038165"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/L00","Source__c":"MONDO:0018181","Xref__c":"L00"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C013206","Source__c":"C0038165; MONDO:0018181","Xref__c":"D013206"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C85077","Source__c":"C0038165; MONDO:0018181","Xref__c":"C85077"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=200946001","Source__c":"C0038165; MONDO:0018181","Xref__c":"200946001"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=52484","Source__c":"C0038165","Xref__c":"MEDGEN:52484"},{"URL__c":"https://www.orpha.net/en/disease/detail/36236","Source__c":"C0038165; MONDO:0018181; ORPHA:36236","Xref__c":"ORPHA:36236"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A9063","Source__c":"MONDO:0018181","Xref__c":"DOID:9063"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=277475006","Source__c":"MONDO:0018181","Xref__c":"277475006"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018181","Source__c":"GARD:0013158","Xref__c":"MONDO:0018181"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Bacterial Infectious Disease"]},"synonyms":["dermatitis exfoliativa neonatorum"," generalised exfoliative disease"," generalized exfoliative disease"," pemphigus neonatorum"," ritter disease"," ritter's disease"," scalded skin syndrome"," ssss"," ssss - staphylococcal scalded skin syndrome"," toxic epidermal necrolysis, subcorneal type"]}