{"Name":"Marginal zone lymphoma","DiseaseID__c":"GARD:0013237","id":13237,"encodedName":"marginal-zone-lymphoma","IsDeleted":false,"Disease_Name_Full__c":"Marginal zone lymphoma","Xref_IDs__c":"447100004; C1367654; C4341; DOID:0050748; MEDGEN:277950; MONDO:0017604; ORPHA:300912","USA_Estimate__c":"50,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"80,000 to 800,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0017604","Disease_Description__c":"A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of extranodal disease; and splenic marginal zone B-cell lymphoma, which affects the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood.","GARD_Name__c":"Marginal zone lymphoma","GARD_Synonym__c":"lymphoma of marginal zone b cell; marginal zone b cell lymphoma; marginal zone b-cell lymphoma; mzbcl; mzl","Curated_Disease_Description_Source__c":"MONDO:0017604","Curated_Disease_Description__c":"A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of extranodal disease; and splenic marginal zone B-cell lymphoma, which affects the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"50,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:300912","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0017604","ORPHANET_ID__c":"ORPHA:300912","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Linfoma de la zona marginal","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"linfoma de la zona marginal","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A usually indolent mature B-cell lymphoma, arising from the marginal zone of lymphoid tissues. It is characterized by the presence of small to medium sized atypical lymphocytes. It comprises three entities, according to the anatomic sites involved: extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue, which affects extranodal sites (most often stomach, lung, skin, and ocular adnexa); nodal marginal zone B-cell lymphoma, which affects lymph nodes without evidence of extranodal disease; and splenic marginal zone B-cell lymphoma, which affects the spleen and splenic hilar lymph nodes, bone marrow, and often the peripheral blood.","Curated_Disease_Description_Source__c":"MONDO:0017604","GARD_Synonym__c":"lymphoma of marginal zone b cell; marginal zone b cell lymphoma; marginal zone b-cell lymphoma; mzbcl; mzl","Name":"Marginal zone lymphoma","Curated_USA_Estimate__c":"50,000","estimateUsa":"50,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Lymphoma Research Foundation","Website__c":"https://lymphoma.org/"},{"Account_Name__c":"HealthTree Foundation","Website__c":"https://healthtree.org/"},{"Account_Name__c":"Lymphoma Coalition","Website__c":"https://lymphomacoalition.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Hematology","Tag_Category__c":"Disease Category;Specialist","category_description":"Blood diseases affect the blood or blood-forming organs, including red blood cells, white blood cells, platelets, plasma, and bone marrow.","curated_tag_name":"Blood diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:300912"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1367654","Source__c":"C1367654","Xref__c":"C1367654"},{"URL__c":"https://www.orpha.net/en/disease/detail/300912","Source__c":"C1367654; MONDO:0017604","Xref__c":"ORPHA:300912"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=277950","Source__c":"C1367654","Xref__c":"MEDGEN:277950"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=447100004","Source__c":"C1367654; MONDO:0017604","Xref__c":"447100004"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0050748","Source__c":"MONDO:0017604","Xref__c":"DOID:0050748"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C4341","Source__c":"C1367654; MONDO:0017604","Xref__c":"C4341"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0017604","Source__c":"GARD:0013237","Xref__c":"MONDO:0017604"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=128803008","Source__c":"C1367654","Xref__c":"128803008"}],"tags":{"Specialist":["Cancer - Oncologist","Hematology"],"Disease Category":["Cancer","Hematology"]},"synonyms":["lymphoma of marginal zone b cell"," marginal zone b cell lymphoma"," marginal zone b-cell lymphoma"," mzbcl"," mzl"]}