{"Name":"Pneumonia caused by pseudomonas aeruginosa infection","DiseaseID__c":"GARD:0013613","id":13613,"encodedName":"pneumonia-caused-by-pseudomonas-aeruginosa-infection","IsDeleted":false,"Disease_Name_Full__c":"Pneumonia caused by pseudomonas aeruginosa infection","Xref_IDs__c":"C0920182; MEDGEN:852026; MONDO:0037398; ORPHA:90066","USA_Estimate__c":"200,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"800,000 to 5,000,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0037398","Disease_Description__c":"A rare pulmonary disease characterized by primary or nonbacteremic pneumonia most frequently arising in an intensive care setting, or bacteremic pneumonia, which is typically associated with neutropenia. Chronic lower respiratory tract infection with development of episodes of pneumonia is common in patients with cystic fibrosis. Acute infections are potentially life-threatening. Patients present with fever, chills, dyspnea, cyanosis, productive cough, as well as signs of severe systemic toxicity. Alveolar hemorrhage, necrosis, and, eventually, cavity formation, are commonly seen.","GARD_Name__c":"Pneumonia caused by pseudomonas aeruginosa infection","GARD_Synonym__c":null,"Curated_Disease_Description_Source__c":"PlainLanguagePilotV1-Sep23","Curated_Disease_Description__c":"Pneumonia caused by Pseudomonas aeruginosa infection is a rare lung disease that can happen in two ways. Primary pneumonia usually happens in the intensive care unit and is not caused by bacteria in the blood. Bacteremic pneumonia is caused by bacteria in the blood and is usually seen in people with low white blood cell counts. This can commonly cause infection in people with cystic fibrosis. They may have chronic infections in their lungs and can develop pneumonia episodes. Symptoms of this type of pneumonia include: fever, chills, shortness of breath, bluish skin color, coughing up mucus, and feeling very sick. This type of pneumonia can be very dangerous and even life-threatening. It can cause bleeding and damage in the lungs.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"200,000","Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:90066","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0037398","ORPHANET_ID__c":"ORPHA:90066","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Neumonía causada por infección por pseudomonas aeruginosa","Spanish_Description_Source__c":"ORPHA:90066","Spanish_Description__c":"Es una enfermedad pulmonar poco frecuente caracterizada por neumonía primaria o no bacteriémica que se produce con mayor frecuencia en el contexto de cuidados intensivos, o una neumonía bacteriémica, y que suele estar asociada a neutropenia. La infección crónica de las vías respiratorias bajas con desarrollo de episodios de neumonía es común en pacientes con fibrosis quística. Las infecciones agudas son potencialmente mortales. Los pacientes presentan fiebre, escalofríos, disnea, cianosis y tos productiva, así como signos de toxicidad sistémica grave. Suele observarse hemorragias alveolares, necrosis y, finalmente, formación de cavidades.","Spanish_Disease_Name__c":"neumonía causada por infección por pseudomonas aeruginosa","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:97955","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Pneumonia caused by Pseudomonas aeruginosa infection is a rare lung disease that can happen in two ways. Primary pneumonia usually happens in the intensive care unit and is not caused by bacteria in the blood. Bacteremic pneumonia is caused by bacteria in the blood and is usually seen in people with low white blood cell counts. This can commonly cause infection in people with cystic fibrosis. They may have chronic infections in their lungs and can develop pneumonia episodes. Symptoms of this type of pneumonia include: fever, chills, shortness of breath, bluish skin color, coughing up mucus, and feeling very sick. This type of pneumonia can be very dangerous and even life-threatening. It can cause bleeding and damage in the lungs.","Curated_Disease_Description_Source__c":"PlainLanguagePilotV1-Sep23","Name":"Pneumonia caused by pseudomonas aeruginosa infection","Curated_USA_Estimate__c":"200,000","estimateUsa":"200,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Pulmonology","Tag_Category__c":"Disease Category;Specialist","category_description":"Respiratory diseases affect the nose, mouth, throat, voice box, windpipe, lungs, or blood vessels.","curated_tag_name":"Respiratory diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:90066"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0920182","Source__c":"C0920182","Xref__c":"C0920182"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=852026","Source__c":"C0920182","Xref__c":"MEDGEN:852026"},{"URL__c":"https://www.orpha.net/en/disease/detail/90066","Source__c":"C0920182; MONDO:0037398; ORPHA:90066","Xref__c":"ORPHA:90066"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0037398","Source__c":"GARD:0013613","Xref__c":"MONDO:0037398"}],"tags":{"Disease Category":["Pulmonology"],"Specialist":["Pulmonology","Pediatrics"]},"synonyms":[""]}