{"Name":"Short bowel syndrome","DiseaseID__c":"GARD:0001502","id":1502,"encodedName":"short-bowel-syndrome","IsDeleted":false,"Disease_Name_Full__c":"Short bowel syndrome","Xref_IDs__c":"26629001; C0036992; C99059; D012778; DOID:10605; MEDGEN:19966; MONDO:0015183; ORPHA:104008","USA_Estimate__c":"50,000","No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":2,"World_Estimate__c":"80,000 to 800,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":2,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0015183","Disease_Description__c":"Short bowel syndrome is an intestinal failure due to either a congenital defect, intestinal infarction or extensive surgical resection of the intestinal tract that results in a functional small intestine of less than 200cm in length and is characterized by diarrhea, nutrient malabsoption, bowel dilation and dysmobility.","GARD_Name__c":"Short bowel syndrome","GARD_Synonym__c":"acquired short bowel syndrome; post-resection short bowel syndrome; sbs - short bowel syndrome; sgs - short gut syndrome; short gut syndrome; short intestine syndrome","Curated_Disease_Description_Source__c":"GARD:0001502","Curated_Disease_Description__c":"Short bowel syndrome is a disorder characterized by malabsorption of nutrients due to problems involving the small intestine. The small intestine is the tube-shaped organ between the stomach and large intestine, which includes the duodenum, jejunum, and ileum, where most food digestion and nutrient absorption take place. The causes of Short bowel syndrome in adults include Crohn disease, mesenteric ischemia, radiation enteritis, or surgical removal of half or more of the small intestine to treat intestinal diseases or injuries. In children the main causes include necrotizing enterocolitis, intestinal atresias, and intestinal volvulus. Signs and symptoms may include diarrhea, cramping, bloating, heartburn, dehydration, malnutrition, weight loss, food sensitivities, weakness, and fatigue.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"50,000","Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:104008","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0015183","ORPHANET_ID__c":"ORPHA:104008","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Síndrome del intestino corto","Spanish_Description_Source__c":"ORPHA:104008","Spanish_Description__c":"El síndrome del intestino corto es un fallo intestinal ya sea debido a un defecto congénito, a un infarto intestinal o una resección quirúrgica extensiva intestinal, que da lugar a un intestino funcional pequeño de menos de 200 cm de longitud y que se caracteriza por diarrea, malabsorción de nutrientes, dilatación intestinal y dismovilidad.","Spanish_Disease_Name__c":"síndrome del intestino corto","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:97935","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Short bowel syndrome is a disorder characterized by malabsorption of nutrients due to problems involving the small intestine. The small intestine is the tube-shaped organ between the stomach and large intestine, which includes the duodenum, jejunum, and ileum, where most food digestion and nutrient absorption take place. The causes of Short bowel syndrome in adults include Crohn disease, mesenteric ischemia, radiation enteritis, or surgical removal of half or more of the small intestine to treat intestinal diseases or injuries. In children the main causes include necrotizing enterocolitis, intestinal atresias, and intestinal volvulus. Signs and symptoms may include diarrhea, cramping, bloating, heartburn, dehydration, malnutrition, weight loss, food sensitivities, weakness, and fatigue.","Curated_Disease_Description_Source__c":"GARD:0001502","GARD_Synonym__c":"acquired short bowel syndrome; post-resection short bowel syndrome; sbs - short bowel syndrome; sgs - short gut syndrome; short gut syndrome; short intestine syndrome","Name":"Short bowel syndrome","Curated_USA_Estimate__c":"50,000","estimateUsa":"50,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Alianza Iberoamericana de Enfermedades Raras o Poco Frecuentes","Website__c":"https://aliber.org/web/"},{"Account_Name__c":"Federación Mexicana de Enfermedades Raras (FEMEXER)","Website__c":"http://www.femexer.org/"},{"Account_Name__c":"Federación Española de Enfermedades Raras","Website__c":"https://enfermedades-raras.org/"},{"Account_Name__c":"Federación Colombiana de Enfermedades Raras","Website__c":"http://www.fecoer.org"},{"Account_Name__c":"Federación Argentina de Enfermedades Poco Frecuentes","Website__c":"https://fadepof.org.ar/"},{"Account_Name__c":"Asociación Todos Unidos Enfermedades Raras Uruguay","Website__c":"https://atueru.org.uy/"},{"Account_Name__c":"AGA GI Patient Center","Website__c":"https://patient.gastro.org/"},{"Account_Name__c":"International Foundation for Functional Gastrointestinal Disorders","Website__c":"https://iffgd.org/"},{"Account_Name__c":"Association of Gastrointestinal Motility Disorders","Website__c":"https://www.agmdhope.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Gastroenterology","Tag_Category__c":"Disease Category;Specialist","category_description":"Gastrointestinal diseases, or digestive diseases, affect the esophagus, stomach, small intestine, large intestine, liver, gallbladder, or pancreas.","curated_tag_name":"Gastrointestinal diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=19966","Source__c":"C0036992","Xref__c":"MEDGEN:19966"},{"URL__c":"https://www.orpha.net/en/disease/detail/104008","Source__c":"C0036992; MONDO:0015183; ORPHA:104008","Xref__c":"ORPHA:104008"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0036992","Source__c":"C0036992","Xref__c":"C0036992"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C012778","Source__c":"C0036992; MONDO:0015183","Xref__c":"D012778"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C99059","Source__c":"C0036992; MONDO:0015183","Xref__c":"C99059"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=26629001","Source__c":"C0036992; MONDO:0015183","Xref__c":"26629001"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A10605","Source__c":"MONDO:0015183","Xref__c":"DOID:10605"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=235724004","Source__c":"C0036992","Xref__c":"235724004"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0015183","Source__c":"GARD:0001502","Xref__c":"MONDO:0015183"},{"URL__c":"https://oley.org/page/FDA_Patient_Listening_Session_on_SBS"},{"URL__c":"https://www.niddk.nih.gov/health-information/digestive-diseases/short-bowel-syndrome"}],"tags":{"Disease Category":["Gastroenterology"],"Specialist":["Gastroenterology"]},"synonyms":["acquired short bowel syndrome"," post-resection short bowel syndrome"," sbs - short bowel syndrome"," sgs - short gut syndrome"," short gut syndrome"," short intestine syndrome"],"spanishId":13306,"spanishName":"sindrome-del-intestino-corto"}