{"Name":"Toxocariasis","DiseaseID__c":"GARD:0018793","id":18793,"encodedName":"toxocariasis","IsDeleted":false,"Disease_Name_Full__c":"Toxocariasis","Xref_IDs__c":"406619001; C0040553; C34758; C85194; D014120; DOID:9790; MEDGEN:21596; MONDO:0005988; ORPHA:3343","USA_Estimate__c":"50,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":"80,000 to 800,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0005988","Disease_Description__c":"A parasitic infection caused by worms found in domestic animals. In humans nematode larvae enter the portal system from the small intestine and disseminate in visceral organs causing inflammatory reactions. Signs and symptoms include eosinophilia, hepatomegaly, splenomegaly, and lung infections.","GARD_Name__c":"Toxocariasis","GARD_Synonym__c":"infection by toxascaris; infection caused by toxocara; toxocara caused disease or disorder; toxocara disease or disorder; toxocara infection; toxocara infectious disease; visceral larva migrans","Curated_Disease_Description_Source__c":"ORPHA:3343","Curated_Disease_Description__c":"A cosmopolitan zoonotic disease caused in humans by the accidental ingestion of eggs or larvae of the ascarids <i>Toxocara canis</i> or <i>Toxocara cati</i>, the common round worm of dogs and cats respectively. The infestation can be asymptomatic or can present as visceral larva migrans caused by larval migration through major organs such as liver, lungs or central nervous system (manifesting with fever, cough, hepatomegaly, pneumonia or rarely encephalitis), or as ocular larva migrans caused by larval migration to the eye (manifesting as ocular inflammation and retinal scaring).","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"50,000","Age_at_Onset_Snippet_Text__c":"as a Child","SourceID__c":"ORPHA:3343","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0005988","ORPHANET_ID__c":"ORPHA:3343","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Toxocariasis","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"toxocariasis","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A cosmopolitan zoonotic disease caused in humans by the accidental ingestion of eggs or larvae of the ascarids <i>Toxocara canis</i> or <i>Toxocara cati</i>, the common round worm of dogs and cats respectively. The infestation can be asymptomatic or can present as visceral larva migrans caused by larval migration through major organs such as liver, lungs or central nervous system (manifesting with fever, cough, hepatomegaly, pneumonia or rarely encephalitis), or as ocular larva migrans caused by larval migration to the eye (manifesting as ocular inflammation and retinal scaring).","Curated_Disease_Description_Source__c":"ORPHA:3343","GARD_Synonym__c":"infection by toxascaris; infection caused by toxocara; toxocara caused disease or disorder; toxocara disease or disorder; toxocara infection; toxocara infectious disease; visceral larva migrans","Name":"Toxocariasis","Curated_USA_Estimate__c":"50,000","estimateUsa":"50,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Parasitic Disease","Tag_Category__c":"Cause","curated_tag_name":"Parasitic Infectious Diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:3343"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A9790","Source__c":"MONDO:0005988","Xref__c":"DOID:9790"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0040553","Source__c":"C0040553","Xref__c":"C0040553"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C85194","Source__c":"C0040553; MONDO:0005988","Xref__c":"C85194"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C014120","Source__c":"C0040553; MONDO:0005988","Xref__c":"D014120"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C34758","Source__c":"MONDO:0005988","Xref__c":"C34758"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=21596","Source__c":"C0040553","Xref__c":"MEDGEN:21596"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=406619001","Source__c":"C0040553; MONDO:0005988","Xref__c":"406619001"},{"URL__c":"https://www.orpha.net/en/disease/detail/3343","Source__c":"C0040553; MONDO:0005988; ORPHA:3343","Xref__c":"ORPHA:3343"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0005988","Source__c":"GARD:0018793","Xref__c":"MONDO:0005988"},{"URL__c":"https://www.cdc.gov/toxocariasis/about/"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Parasitic Disease"]},"synonyms":["infection by toxascaris"," infection caused by toxocara"," toxocara caused disease or disorder"," toxocara disease or disorder"," toxocara infection"," toxocara infectious disease"," visceral larva migrans"]}