{"Name":"Rickettsialpox","DiseaseID__c":"GARD:0019030","id":19030,"encodedName":"rickettsialpox","IsDeleted":false,"Disease_Name_Full__c":"Rickettsialpox","Xref_IDs__c":"75096007; A79.1; C0035597; DOID:11103; MEDGEN:19803; MONDO:0019360; ORPHA:83312","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"ORPHA:83312","Disease_Description__c":"A rare, acquired, self-limiting, infectious disease due to the mite-borne bacteria <i>Rickettsia akari</i> characterized by an asymptomatic, 0.5 to 2 cm in diameter papulovesicle that typically ulcerates and forms an eschar, followed by a generalized papulovesicular rash associating variable constitutional symptoms, such as localized lymphadenopathy, fever, malaise, and headaches. Additonal symptoms may include diaphoresis, myalgia and, less frequently, rhinorrhea, pharyngitis, nausea, vomiting, splenomegaly, conjunctival hyperemia, and abdominal pain. Systemic symptoms resolve within 6-10 days.","GARD_Name__c":"Rickettsialpox","GARD_Synonym__c":"kew gardens spotted fever; rickettsia akari spotted fever; rickettsialpox due to rickettsia akari; vesicular rickettsiosis","Curated_Disease_Description_Source__c":"ORPHA:83312","Curated_Disease_Description__c":"A rare, acquired, self-limiting, infectious disease due to the mite-borne bacteria <i>Rickettsia akari</i> characterized by an asymptomatic, 0.5 to 2 cm in diameter papulovesicle that typically ulcerates and forms an eschar, followed by a generalized papulovesicular rash associating variable constitutional symptoms, such as localized lymphadenopathy, fever, malaise, and headaches. Additonal symptoms may include diaphoresis, myalgia and, less frequently, rhinorrhea, pharyngitis, nausea, vomiting, splenomegaly, conjunctival hyperemia, and abdominal pain.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:83312","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0019360","ORPHANET_ID__c":"ORPHA:83312","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Rickettsiosis exantemática","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"rickettsiosis exantemática","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare, acquired, self-limiting, infectious disease due to the mite-borne bacteria <i>Rickettsia akari</i> characterized by an asymptomatic, 0.5 to 2 cm in diameter papulovesicle that typically ulcerates and forms an eschar, followed by a generalized papulovesicular rash associating variable constitutional symptoms, such as localized lymphadenopathy, fever, malaise, and headaches. Additonal symptoms may include diaphoresis, myalgia and, less frequently, rhinorrhea, pharyngitis, nausea, vomiting, splenomegaly, conjunctival hyperemia, and abdominal pain.","Curated_Disease_Description_Source__c":"ORPHA:83312","GARD_Synonym__c":"kew gardens spotted fever; rickettsia akari spotted fever; rickettsialpox due to rickettsia akari; vesicular rickettsiosis","Name":"Rickettsialpox","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Bacterial Infectious Disease","Tag_Category__c":"Cause","curated_tag_name":"Bacterial Infectious Disease"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:83312"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/83312","Source__c":"C0035597; MONDO:0019360; ORPHA:83312","Xref__c":"ORPHA:83312"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=75096007","Source__c":"C0035597; MONDO:0019360","Xref__c":"75096007"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0035597","Source__c":"C0035597","Xref__c":"C0035597"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A11103","Source__c":"MONDO:0019360","Xref__c":"DOID:11103"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=19803","Source__c":"C0035597","Xref__c":"MEDGEN:19803"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019360","Source__c":"GARD:0019030","Xref__c":"MONDO:0019360"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/A79.1","Source__c":"MONDO:0019360","Xref__c":"A79.1"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Bacterial Infectious Disease"]},"synonyms":["kew gardens spotted fever"," rickettsia akari spotted fever"," rickettsialpox due to rickettsia akari"," vesicular rickettsiosis"]}