{"Name":"Pseudotyphus of California","DiseaseID__c":"GARD:0019034","id":19034,"encodedName":"pseudotyphus-of-california","IsDeleted":false,"Disease_Name_Full__c":"Pseudotyphus of California","Xref_IDs__c":"764104003; C4706680; MEDGEN:1643522; MONDO:0019364; ORPHA:83316","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0019364","Disease_Description__c":"Pseudotyphus of California is a rare, flea-borne Rickettsial disease caused by a <i>Rickettsia felis </i> infection. Patients can be asymptomatic or can present with unspecific symptoms (such as fever, headache, generalized maculopapular rash, myalgia, arthralgia and, ocasionally, eschar, lymphadenopathy, nausea, vomiting, loss of appetite and abdominal pain). Rarely, serious manifestations may occur and include neurological dysfunction (photophobia, hearing loss, and signs of meningitis) and pulmonary compromise.","GARD_Name__c":"Pseudotyphus of California","GARD_Synonym__c":"infection caused by rickettsia felis","Curated_Disease_Description_Source__c":"MONDO:0019364","Curated_Disease_Description__c":"Pseudotyphus of California is a rare, flea-borne Rickettsial disease caused by a Rickettsia felis  infection. Patients can be asymptomatic or can present with unspecific symptoms (such as fever, headache, generalized maculopapular rash, myalgia, arthralgia and, ocasionally, eschar, lymphadenopathy, nausea, vomiting, loss of appetite and abdominal pain). Rarely, serious manifestations may occur and include neurological dysfunction (photophobia, hearing loss, and signs of meningitis) and pulmonary compromise.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:83316","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0019364","ORPHANET_ID__c":"ORPHA:83316","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Pseudotifus de califonia","Spanish_Description_Source__c":"ORPHA:83316","Spanish_Description__c":"El pseudotifus de California es una enfermedad poco frecuente. Esta infección es transmitida por pulgas y causada por <i> Rickettsia felis </ i>. Los afectados pueden ser asintomáticos o presentar síntomas inespecíficos (tales como fiebre, dolor de cabeza, erupción maculopapular generalizada, mialgias, artralgias y, ocasionalmente, escaras, linfadenopatía, náuseas, vómitos, pérdida de apetito y dolor abdominal). En raras ocasiones, pueden presentarse manifestaciones graves que incluyen disfunción neurológica (fotofobia, pérdida de audición y signos de meningitis) y compromiso pulmonar.","Spanish_Disease_Name__c":"pseudotifus de califonia","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Pseudotyphus of California is a rare, flea-borne Rickettsial disease caused by a Rickettsia felis  infection. Patients can be asymptomatic or can present with unspecific symptoms (such as fever, headache, generalized maculopapular rash, myalgia, arthralgia and, ocasionally, eschar, lymphadenopathy, nausea, vomiting, loss of appetite and abdominal pain). Rarely, serious manifestations may occur and include neurological dysfunction (photophobia, hearing loss, and signs of meningitis) and pulmonary compromise.","Curated_Disease_Description_Source__c":"MONDO:0019364","GARD_Synonym__c":"infection caused by rickettsia felis","Name":"Pseudotyphus of California","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Bacterial Infectious Disease","Tag_Category__c":"Cause","curated_tag_name":"Bacterial Infectious Disease"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:83316"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=764104003","Source__c":"C4706680; MONDO:0019364","Xref__c":"764104003"},{"URL__c":"https://www.orpha.net/en/disease/detail/83316","Source__c":"C4706680; MONDO:0019364; ORPHA:83316","Xref__c":"ORPHA:83316"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C4706680","Source__c":"C4706680","Xref__c":"C4706680"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1643522","Source__c":"C4706680","Xref__c":"MEDGEN:1643522"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019364","Source__c":"GARD:0019034","Xref__c":"MONDO:0019364"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Bacterial Infectious Disease"]},"synonyms":["infection caused by rickettsia felis"]}