{"Name":"Progressive rubella panencephalitis","DiseaseID__c":"GARD:0019043","id":19043,"encodedName":"progressive-rubella-panencephalitis","IsDeleted":false,"Disease_Name_Full__c":"Progressive rubella panencephalitis","Xref_IDs__c":"10082001; C1305924; MEDGEN:726815; MONDO:0019386; ORPHA:83616","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":4,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0019386","Disease_Description__c":"A neurological disorder arising from primary rubella infection of the brain, characterized by chronic encephalitis. It is believed to be due to a persistence or reactivation of rubella virus infection. It usually manifesting between 8–19 years of age.","GARD_Name__c":"Progressive rubella panencephalitis","GARD_Synonym__c":"rubella panencephalitis","Curated_Disease_Description_Source__c":"ORPHA:83616","Curated_Disease_Description__c":"A rare chronic encephalitis developing up to several years after congenital rubella virus infection or rubella infection in childhood, characterized by slowly progressive, wide-spread neurological symptoms, like cognitive decline, cerebellar ataxia, spasticity, and seizures, amongst others. Progredient deterioration of the neurological disease eventually leads to the death of the patient.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"as a Child","SourceID__c":"ORPHA:83616","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0019386","ORPHANET_ID__c":"ORPHA:83616","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Panencefalitis por rubéola","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"panencefalitis por rubéola","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare chronic encephalitis developing up to several years after congenital rubella virus infection or rubella infection in childhood, characterized by slowly progressive, wide-spread neurological symptoms, like cognitive decline, cerebellar ataxia, spasticity, and seizures, amongst others. Progredient deterioration of the neurological disease eventually leads to the death of the patient.","Curated_Disease_Description_Source__c":"ORPHA:83616","GARD_Synonym__c":"rubella panencephalitis","Name":"Progressive rubella panencephalitis","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"},{"Tag_Name__c":"Rare Viral Disease","Tag_Category__c":"Cause","curated_tag_name":"Viral Infectious Diseases"},{"Tag_Name__c":"Epilepsy","Tag_Category__c":"Account;Specialist","curated_tag_name":"Epilepsy"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:83616"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=726815","Source__c":"C1305924","Xref__c":"MEDGEN:726815"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=10082001","Source__c":"C1305924; MONDO:0019386","Xref__c":"10082001"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1305924","Source__c":"C1305924","Xref__c":"C1305924"},{"URL__c":"https://www.orpha.net/en/disease/detail/83616","Source__c":"C1305924; MONDO:0019386","Xref__c":"ORPHA:83616"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019386","Source__c":"GARD:0019043","Xref__c":"MONDO:0019386"}],"tags":{"Disease Category":["Infectious Disease","Neurology"],"Specialist":["Infectious Disease","Neurology","Epilepsy","Pediatrics"],"Cause":["Rare Viral Disease"],"Account":["Epilepsy"]},"synonyms":["rubella panencephalitis"]}