{"Name":"Growth disorder","DiseaseID__c":"GARD:0020012","id":20012,"encodedName":"growth-disorder","IsDeleted":false,"Disease_Name_Full__c":"Hereditary endocrine growth disease","Xref_IDs__c":"C5680637; D006130; MEDGEN:1842942; MONDO:0015514; ORPHA:156643","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":0,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"ORPHA:156643","Disease_Description__c":null,"GARD_Name__c":"Growth disorder","GARD_Synonym__c":"genetic endocrine growth disease; Hereditary endocrine growth disease","Curated_Disease_Description_Source__c":"ORPHA:156643","Curated_Disease_Description__c":"Does your child seem much shorter - or much taller - than other kids his or her age? It could be normal. Some children may be small for their age but still be developing normally. Some children are short or tall because their parents are.\r\n\r\nBut some children have growth disorders. Growth disorders are problems that prevent children from developing normal height, weight, sexual maturity or other features.\r\n\r\nVery slow or very fast growth can sometimes signal a gland problem or disease.\r\n\r\nThe pituitary gland makes growth hormone, which stimulates the growth of bone and other tissues. Children who have too little of it may be very short. Treatment with growth hormone can stimulate growth.\r\n\r\nPeople can also have too much growth hormone. Usually the cause is a pituitary gland tumor, which is not cancer. Too much growth hormone can cause gigantism in children, where their bones and their body grow too much. In adults, it can cause acromegaly, which makes the hands, feet and face larger than normal. Possible treatments include surgery to remove the tumor, medicines, and radiation therapy.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:156643","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0015514","ORPHANET_ID__c":"ORPHA:156643","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Enfermedad endocrina genética del crecimiento","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"enfermedad endocrina genética del crecimiento","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:97978","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Does your child seem much shorter - or much taller - than other kids his or her age? It could be normal. Some children may be small for their age but still be developing normally. Some children are short or tall because their parents are.\r\n\r\nBut some children have growth disorders. Growth disorders are problems that prevent children from developing normal height, weight, sexual maturity or other features.\r\n\r\nVery slow or very fast growth can sometimes signal a gland problem or disease.\r\n\r\nThe pituitary gland makes growth hormone, which stimulates the growth of bone and other tissues. Children who have too little of it may be very short. Treatment with growth hormone can stimulate growth.\r\n\r\nPeople can also have too much growth hormone. Usually the cause is a pituitary gland tumor, which is not cancer. Too much growth hormone can cause gigantism in children, where their bones and their body grow too much. In adults, it can cause acromegaly, which makes the hands, feet and face larger than normal. Possible treatments include surgery to remove the tumor, medicines, and radiation therapy.","Curated_Disease_Description_Source__c":"ORPHA:156643","GARD_Synonym__c":"genetic endocrine growth disease; Hereditary endocrine growth disease","Name":"Hereditary endocrine growth disease","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Genetics","Tag_Category__c":"Cause;Disease Category;Specialist","category_description":"Genetic diseases affect the DNA, or genetic instructions, which directs how tissues, organs, and body systems function.","curated_tag_name":"Genetic diseases"},{"Tag_Name__c":"Endocrine","Tag_Category__c":"Disease Category;Specialist","category_description":"Endocrine diseases affect hormone production or how the body responds to a specific hormone(s).","curated_tag_name":"Endocrine diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C006130","Source__c":"MONDO:0015514","Xref__c":"D006130"},{"URL__c":"https://www.orpha.net/en/disease/detail/156643","Source__c":"C5680637; MONDO:0015514; ORPHA:156643","Xref__c":"ORPHA:156643"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5680637","Source__c":"C5680637","Xref__c":"C5680637"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1842942","Source__c":"C5680637","Xref__c":"MEDGEN:1842942"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0015514","Source__c":"GARD:0020012","Xref__c":"MONDO:0015514"},{"URL__c":"https://medlineplus.gov/growthdisorders.html"}],"tags":{"Cause":["Genetics"],"Disease Category":["Genetics","Endocrine"],"Specialist":["Genetics","Endocrine"]},"synonyms":["genetic endocrine growth disease"," Hereditary endocrine growth disease"]}