{"Name":"Cavitary myiasis","DiseaseID__c":"GARD:0020066","id":20066,"encodedName":"cavitary-myiasis","IsDeleted":false,"Disease_Name_Full__c":"Cavitary myiasis","Xref_IDs__c":"764811001; C4707154; MEDGEN:1631496; MONDO:0015623; ORPHA:165958","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":4,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0015623","Disease_Description__c":"Cavitary myiasis is a rare parasitic disease characterized by the infestation of natural body cavities (e.g. aural, nasal, oral, urogenital myiasis) and internal organs (e.g. cerebral myiasis, ophthalmomyiasis, intestinal and tracheopulmonary myiasis) with dipteran larvae. Clinical presentation is variable depending on the affected site(s) and degree of infestation and include foreign-body sensation (with or without movement sensation), hemorrhage, pain, edema, sensory loss, malodor, and pruritus, among others. Neurological features (e.g. motor deficits, seizures, reduced mental status, extrapyramidal signs) have been reported in cerebral myiasis.","GARD_Name__c":"Cavitary myiasis","GARD_Synonym__c":"infestation of body cavity caused by fly larvae","Curated_Disease_Description_Source__c":"ORPHA:165958","Curated_Disease_Description__c":"Cavitary myiasis is a rare parasitic disease characterized by the infestation of natural body cavities (e.g., aural, nasal, oral, urogenital myiasis) and internal organs (e.g., cerebral myiasis, ophthalmomyiasis, intestinal and tracheopulmonary myiasis) with dipteran larvae. Clinical presentation is variable depending on the affected site(s) and degree of infestation and include foreign-body sensation (with or without movement sensation), hemorrhage, pain, edema, sensory loss, malodor, and pruritus, among others. Neurological features (e.g., motor deficits, seizures, reduced mental status, extrapyramidal signs) have been reported in cerebral myiasis.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:165958","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0015623","ORPHANET_ID__c":"ORPHA:165958","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Miasis cavitaria","Spanish_Description_Source__c":"ORPHA:165958","Spanish_Description__c":"Es una enfermedad parasitaria poco frecuente, caracterizada por la infestación, por larvas de dípteros, de cavidades naturales del cuerpo (por ejemplo, miasis auditiva, nasal, oral, urogenital) y de órganos internos (por ejemplo, miasis cerebral, oftalmomiasis, miasis intestinal y traqueopulmonar). La presentación clínica es variable según los sitios afectados y el grado de infestación, e incluye sensación de cuerpo extraño (con o sin sensación de movimiento), hemorragia, dolor, edema, pérdida sensorial, mal olor y prurito, entre otros. En los casos de miasis cerebral, también se han notificado características neurológicas (por ejemplo, deficiencias motoras, convulsiones, estado mental reducido, signos extrapiramidales).","Spanish_Disease_Name__c":"miasis cavitaria","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Cavitary myiasis is a rare parasitic disease characterized by the infestation of natural body cavities (e.g., aural, nasal, oral, urogenital myiasis) and internal organs (e.g., cerebral myiasis, ophthalmomyiasis, intestinal and tracheopulmonary myiasis) with dipteran larvae. Clinical presentation is variable depending on the affected site(s) and degree of infestation and include foreign-body sensation (with or without movement sensation), hemorrhage, pain, edema, sensory loss, malodor, and pruritus, among others. Neurological features (e.g., motor deficits, seizures, reduced mental status, extrapyramidal signs) have been reported in cerebral myiasis.","Curated_Disease_Description_Source__c":"ORPHA:165958","GARD_Synonym__c":"infestation of body cavity caused by fly larvae","Name":"Cavitary myiasis","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Ophthalmology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Retinal","Tag_Category__c":"Account;Specialist","curated_tag_name":"Retinal disorders"},{"Tag_Name__c":"Rare Parasitic Disease","Tag_Category__c":"Cause","curated_tag_name":"Parasitic Infectious Diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:165958"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C4707154","Source__c":"C4707154","Xref__c":"C4707154"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1631496","Source__c":"C4707154","Xref__c":"MEDGEN:1631496"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=764811001","Source__c":"C4707154; MONDO:0015623","Xref__c":"764811001"},{"URL__c":"https://www.orpha.net/en/disease/detail/165958","Source__c":"C4707154; MONDO:0015623; ORPHA:165958","Xref__c":"ORPHA:165958"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0015623","Source__c":"GARD:0020066","Xref__c":"MONDO:0015623"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Ophthalmology","Retinal","Pediatrics"],"Account":["Retinal"],"Cause":["Rare Parasitic Disease"]},"synonyms":["infestation of body cavity caused by fly larvae"]}