{"Name":"Malignant peritoneal mesothelioma","DiseaseID__c":"GARD:0020102","id":20102,"encodedName":"malignant-peritoneal-mesothelioma","IsDeleted":false,"Disease_Name_Full__c":"Malignant peritoneal mesothelioma","Xref_IDs__c":"423022270; C0346109; C8704; C9350; DOID:1788; MEDGEN:83406; MONDO:0005512; ORPHA:168811","USA_Estimate__c":"5,000","No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":"8,000 to 80,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0005512","Disease_Description__c":"An aggressive malignant mesothelioma that arises from the peritoneum. Patients usually present with abdominal pain and ascites.","GARD_Name__c":"Malignant peritoneal mesothelioma","GARD_Synonym__c":"advanced malignant mesothelioma of peritoneum; advanced malignant mesothelioma of the peritoneum; advanced malignant peritoneal mesothelioma; advanced peritoneal malignant mesothelioma; cancer of the peritoneum, mesothelioma; diffuse malignant peritoneal mesothelioma; malignant mesothelioma (disease) of peritoneum; malignant mesothelioma of peritoneum; malignant peritoneal mesothelioma, advanced; peritoneal mesothelioma; peritoneal mesothelioma (disease), malignant; peritoneum malignant mesothelioma (disease); primary malignant peritoneal mesothelioma","Curated_Disease_Description_Source__c":"MONDO:0005512","Curated_Disease_Description__c":"An aggressive malignant mesothelioma that arises from the peritoneum. Patients usually present with abdominal pain and ascites.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"5,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:168811","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0005512","ORPHANET_ID__c":"ORPHA:168811","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Mesotelioma peritoneal maligno","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"mesotelioma peritoneal maligno","Spanish_GARD_Synonym__c":"mesotelioma peritoneal maligno difuso; mesotelioma peritoneal maligno primario","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"An aggressive malignant mesothelioma that arises from the peritoneum. Patients usually present with abdominal pain and ascites.","Curated_Disease_Description_Source__c":"MONDO:0005512","GARD_Synonym__c":"advanced malignant mesothelioma of peritoneum; advanced malignant mesothelioma of the peritoneum; advanced malignant peritoneal mesothelioma; advanced peritoneal malignant mesothelioma; cancer of the peritoneum, mesothelioma; diffuse malignant peritoneal mesothelioma; malignant mesothelioma (disease) of peritoneum; malignant mesothelioma of peritoneum; malignant peritoneal mesothelioma, advanced; peritoneal mesothelioma; peritoneal mesothelioma (disease), malignant; peritoneum malignant mesothelioma (disease); primary malignant peritoneal mesothelioma","Name":"Malignant peritoneal mesothelioma","Curated_USA_Estimate__c":"5,000","estimateUsa":"5,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Mesothelioma Guide","Website__c":"https://www.mesotheliomaguide.com/"},{"Account_Name__c":"Mesothelioma.net","Website__c":"https://mesothelioma.net/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:168811"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=83406","Source__c":"C0346109","Xref__c":"MEDGEN:83406"},{"URL__c":"https://www.orpha.net/en/disease/detail/168811","Source__c":"C0346109; MONDO:0005512; ORPHA:168811","Xref__c":"ORPHA:168811"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0346109","Source__c":"C0346109","Xref__c":"C0346109"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C8704","Source__c":"MONDO:0005512","Xref__c":"C8704"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A1788","Source__c":"MONDO:0005512","Xref__c":"DOID:1788"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C9350","Source__c":"C0346109","Xref__c":"C9350"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0005512","Source__c":"GARD:0020102","Xref__c":"MONDO:0005512"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=109853004","Source__c":"C0346109","Xref__c":"109853004"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0100003","Source__c":"C0346109","Xref__c":"HP:0100003"},{"URL__c":"https://secure.ssa.gov/apps10/poms.nsf/lnx/0423022270","Xref__c":"423022270"}],"Inheritance__c":["Non-Mendelian inheritance"],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Accumulation of fluid in the peritoneal cavity (between the layers of the peritoneum that lines the abdomen).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001541","HPO_Synonym__c":"Accumulation of fluid in the abdomen; Peritoneal effusion","HPO_Name__c":"Ascites","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Distention of the abdomen.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0003270","HPO_Synonym__c":"Abdominal bloating; Abdominal distension; Abdominal swelling; Belly bloating; Bloating; Distended abdomen","HPO_Name__c":"Abdominal distention","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002027","HPO_Synonym__c":"Abdominal pain; Pain in stomach; Stomach pain","HPO_Name__c":"Abdominal pain","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Inflammation of the peritoneum.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002586","HPO_Synonym__c":"Inflammation of the peritoneum","HPO_Name__c":"Peritonitis","Feature_System__c":"Immune System; Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002664","HPO_Synonym__c":"Neoplasia; Oncological abnormality; Tumor; Tumour","HPO_Name__c":"Neoplasm","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"An abnormal accumulation of excess fluid in the lower extremity resulting in swelling of the feet and extending upward to the lower leg.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0010741","HPO_Synonym__c":"Edema of the lower limbs; Fluid accumulation in lower limbs; Leg edema; Lower leg swelling; Peripheral edema of lower extremity","HPO_Name__c":"Pedal edema","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"An abnormality of the process of blood coagulation. That is, altered ability or inability of the blood to clot.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001928","HPO_Synonym__c":"Abnormal blood coagulation studies; Coagulation abnormalities; Coagulation abnormality; Haemorrhagic disorders","HPO_Name__c":"Abnormality of coagulation","Feature_System__c":"Blood and Blood-Forming Tissue","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"Difficult or labored breathing. Dyspnea is a subjective feeling only the patient can rate, e.g., on a Borg scale.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002094","HPO_Synonym__c":"Abnormal breathing; Breathing difficulty; Difficult to breathe; Difficulty breathing; Shortness of breath; Trouble breathing","HPO_Name__c":"Dyspnea","Feature_System__c":"Respiratory system","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"Acute obstruction of the intestines preventing passage of the contents of the intestines.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002595","HPO_Synonym__c":"Gastrointestinal atony","HPO_Name__c":"Ileus","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168811","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Reduction of total body weight.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001824","HPO_Synonym__c":"Loss of weight","HPO_Name__c":"Weight loss","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Cancer - Oncologist"],"Disease Category":["Cancer"]},"synonyms":["advanced malignant mesothelioma of peritoneum"," advanced malignant mesothelioma of the peritoneum"," advanced malignant peritoneal mesothelioma"," advanced peritoneal malignant mesothelioma"," cancer of the peritoneum, mesothelioma"," diffuse malignant peritoneal mesothelioma"," malignant mesothelioma (disease) of peritoneum"," malignant mesothelioma of peritoneum"," malignant peritoneal mesothelioma, advanced"," peritoneal mesothelioma"," peritoneal mesothelioma (disease), malignant"," peritoneum malignant mesothelioma (disease)"," primary malignant peritoneal mesothelioma"]}