{"Name":"Primary peritoneal carcinoma","DiseaseID__c":"GARD:0020103","id":20103,"encodedName":"primary-peritoneal-carcinoma","IsDeleted":false,"Disease_Name_Full__c":"Primary peritoneal carcinoma","Xref_IDs__c":"423022483; C1514428; C40022; HP:0030406; MEDGEN:269516; MONDO:0015686; ORPHA:168829","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":3,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":3,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0015686","Disease_Description__c":"A rare carcinoma that arises from the peritoneum and resembles the malignant surface epithelial-stromal tumors that arise from the ovary. Serous adenocarcinoma is the most common histologic variant. It affects women almost exclusively. The diagnosis of primary peritoneal carcinoma can be made only if both ovaries are not involved by tumor, or, if the ovaries are involved, the tumor is confined to the ovarian surface without invasion of the ovarian stroma and the peritoneal involvement is greater than the ovarian surface involvement.","GARD_Name__c":"Primary peritoneal carcinoma","GARD_Synonym__c":"eoppc; extra-ovarian primary peritoneal carcinoma; ppc; primary peritoneal cancer; primary peritoneal carcinoma (disease); primary peritoneal serous carcinoma; serous surface papillary carcinoma","Curated_Disease_Description_Source__c":"MONDO:0015686","Curated_Disease_Description__c":"A rare carcinoma that arises from the peritoneum and resembles the malignant surface epithelial-stromal tumors that arise from the ovary. Serous adenocarcinoma is the most common histologic variant. It affects women almost exclusively. The diagnosis of primary peritoneal carcinoma can be made only if both ovaries are not involved by tumor, or, if the ovaries are involved, the tumor is confined to the ovarian surface without invasion of the ovarian stroma and the peritoneal involvement is greater than the ovarian surface involvement.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:168829","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0015686","ORPHANET_ID__c":"ORPHA:168829","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Carcinoma primario peritoneal","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"carcinoma primario peritoneal","Spanish_GARD_Synonym__c":"carcinoma papilar de la superficie serosa; carcinoma peritoneal primario seroso; carcinoma primario peritoneal extraovárico; cpp; cppeo; eoppc; ppc","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare carcinoma that arises from the peritoneum and resembles the malignant surface epithelial-stromal tumors that arise from the ovary. Serous adenocarcinoma is the most common histologic variant. It affects women almost exclusively. The diagnosis of primary peritoneal carcinoma can be made only if both ovaries are not involved by tumor, or, if the ovaries are involved, the tumor is confined to the ovarian surface without invasion of the ovarian stroma and the peritoneal involvement is greater than the ovarian surface involvement.","Curated_Disease_Description_Source__c":"MONDO:0015686","GARD_Synonym__c":"eoppc; extra-ovarian primary peritoneal carcinoma; ppc; primary peritoneal cancer; primary peritoneal carcinoma (disease); primary peritoneal serous carcinoma; serous surface papillary carcinoma","Name":"Primary peritoneal carcinoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:168829"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1514428","Source__c":"C1514428","Xref__c":"C1514428"},{"URL__c":"https://www.orpha.net/en/disease/detail/168829","Source__c":"C1514428; MONDO:0015686","Xref__c":"ORPHA:168829"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C40022","Source__c":"C1514428; MONDO:0015686","Xref__c":"C40022"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=269516","Source__c":"C1514428","Xref__c":"MEDGEN:269516"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0015686","Source__c":"GARD:0020103","Xref__c":"MONDO:0015686"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0030406","Source__c":"C1514428","Xref__c":"HP:0030406"},{"URL__c":"https://secure.ssa.gov/apps10/poms.nsf/lnx/0423022483","Xref__c":"423022483"},{"URL__c":"https://www.cancer.gov/types/ovarian"},{"URL__c":"https://www.cancer.gov/types/ovarian/patient/ovarian-epithelial-treatment-pdq"}],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:168829","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An unpleasant sensation characterized by physical discomfort (such as pricking, throbbing, or aching) and perceived to originate in the abdomen.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002027","HPO_Synonym__c":"Abdominal pain; Pain in stomach; Stomach pain","HPO_Name__c":"Abdominal pain","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168829","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Distention of the abdomen.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0003270","HPO_Synonym__c":"Abdominal bloating; Abdominal distension; Abdominal swelling; Belly bloating; Bloating; Distended abdomen","HPO_Name__c":"Abdominal distention","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168829","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002664","HPO_Synonym__c":"Neoplasia; Oncological abnormality; Tumor; Tumour","HPO_Name__c":"Neoplasm","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168829","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Inflammation of the peritoneum.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002586","HPO_Synonym__c":"Inflammation of the peritoneum","HPO_Name__c":"Peritonitis","Feature_System__c":"Immune System; Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168829","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Infrequent or difficult evacuation of feces.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002019","HPO_Synonym__c":"Constipation; Costiveness; Dyschezia","HPO_Name__c":"Constipation","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:168829","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Nausea is a commonly encountered symptom that has been defined as an unpleasant painless subjective feeling that one will imminently vomit. Vomiting has been defined as the forceful expulsion of the contents of the stomach, duodenum, or jejunum through the oral cavity. While nausea and vomiting are often thought to exist on a temporal continuum, this is not always the case. There are situations when severe nausea may be present without emesis and less frequently, when emesis may be present without preceding nausea.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002017","HPO_Synonym__c":"Nausea and vomiting","HPO_Name__c":"Nausea and vomiting","Feature_System__c":"Digestive System","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Cancer - Oncologist"],"Disease Category":["Cancer"]},"synonyms":["eoppc"," extra-ovarian primary peritoneal carcinoma"," ppc"," primary peritoneal cancer"," primary peritoneal carcinoma (disease)"," primary peritoneal serous carcinoma"," serous surface papillary carcinoma"]}