{"Name":"Invasive non-typhoidal salmonellosis","DiseaseID__c":"GARD:0021449","id":21449,"encodedName":"invasive-non-typhoidal-salmonellosis","IsDeleted":false,"Disease_Name_Full__c":"Invasive non-typhoidal salmonellosis","Xref_IDs__c":"763772002; C4706572; MEDGEN:1638286; MONDO:0017944; ORPHA:324648","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0017944","Disease_Description__c":"Invasive non-typhoidal salmonellosis is a rare, bacterial, infectious disease caused by extraintestinal infection of non-typhoidal serotypes of <i> Salmonella enterica </i> in patients with underlying HIV infection, malaria or malignancy. It has a high mortality rate and patients typically present with fever, pallor and respiratory signs (cough, tachypnea, pneumonia). Gastrointestinal manifestations (diarrhea, vomit, abdominal pain) are not common. Occasionally, organ abscesses, septic shock and meningitis may be observed.","GARD_Name__c":"Invasive non-typhoidal salmonellosis","GARD_Synonym__c":"ints (invasive non-typhoidal salmonella) disease; ints disease; invasive non-typhoidal salmonella disease","Curated_Disease_Description_Source__c":"MONDO:0017944","Curated_Disease_Description__c":"Invasive non-typhoidal salmonellosis is a rare, bacterial, infectious disease caused by extraintestinal infection of non-typhoidal serotypes of  Salmonella enterica  in patients with underlying HIV infection, malaria or malignancy. It has a high mortality rate and patients typically present with fever, pallor and respiratory signs (cough, tachypnea, pneumonia). Gastrointestinal manifestations (diarrhea, vomit, abdominal pain) are not common. Occasionally, organ abscesses, septic shock and meningitis may be observed.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:324648","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0017944","ORPHANET_ID__c":"ORPHA:324648","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Salmonelosis invasiva no tifoidea","Spanish_Description_Source__c":"ORPHA:324648","Spanish_Description__c":"La salmonelosis no-tifoidea invasiva es una enfermedad infecciosa bacteriana poco frecuente causada por la infección extraintestinal por serotipos no-tifoideos de <i> Salmonella enterica </ i> en pacientes con infección subyacente por VIH, malaria o patología maligna. Tiene una elevada tasa de mortalidad y, por lo general, los afectados presentan fiebre, palidez y signos respiratorios (tos, taquipnea, neumonía). Las manifestaciones gastrointestinales (diarrea, vómito, dolor abdominal) son poco comunes. Ocasionalmente, se pueden observar abscesos en órganos, choque séptico y meningitis.","Spanish_Disease_Name__c":"salmonelosis invasiva no tifoidea","Spanish_GARD_Synonym__c":"enfermedad de invasiva por salmonella no tifoidea; enfermedad invasiva por snt","Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Invasive non-typhoidal salmonellosis is a rare, bacterial, infectious disease caused by extraintestinal infection of non-typhoidal serotypes of  Salmonella enterica  in patients with underlying HIV infection, malaria or malignancy. It has a high mortality rate and patients typically present with fever, pallor and respiratory signs (cough, tachypnea, pneumonia). Gastrointestinal manifestations (diarrhea, vomit, abdominal pain) are not common. Occasionally, organ abscesses, septic shock and meningitis may be observed.","Curated_Disease_Description_Source__c":"MONDO:0017944","GARD_Synonym__c":"ints (invasive non-typhoidal salmonella) disease; ints disease; invasive non-typhoidal salmonella disease","Name":"Invasive non-typhoidal salmonellosis","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Bacterial Infectious Disease","Tag_Category__c":"Cause","curated_tag_name":"Bacterial Infectious Disease"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:324648"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C4706572","Source__c":"C4706572","Xref__c":"C4706572"},{"URL__c":"https://www.orpha.net/en/disease/detail/324648","Source__c":"C4706572; MONDO:0017944; ORPHA:324648","Xref__c":"ORPHA:324648"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=763772002","Source__c":"C4706572; MONDO:0017944","Xref__c":"763772002"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1638286","Source__c":"C4706572","Xref__c":"MEDGEN:1638286"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0017944","Source__c":"GARD:0021449","Xref__c":"MONDO:0017944"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Bacterial Infectious Disease"]},"synonyms":["ints (invasive non-typhoidal salmonella) disease"," ints disease"," invasive non-typhoidal salmonella disease"]}