{"Name":"Deep dermatophytosis","DiseaseID__c":"GARD:0021631","id":21631,"encodedName":"deep-dermatophytosis","IsDeleted":false,"Disease_Name_Full__c":"Deep dermatophytosis","Xref_IDs__c":"C1395264; C35073; HP:0032515; MEDGEN:235599; MONDO:0021660; ORPHA:397587","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":2,"Description_Source__c":"MONDO:0021660","Disease_Description__c":"A deep folliculitis due to a cutaneous dermatophyte infection, usually on the legs. It is most commonly caused by trichophyton rubrum and is characterized by the formation of spongy granulomas which persist for three to four months and leaves deep scars.","GARD_Name__c":"Deep dermatophytosis","GARD_Synonym__c":"deep seated dermatophytosis; dermatophytic granuloma; dermatophytic mycetoma; dermatophytosis profunda; disseminated granulomatous dermatophytosis; granuloma trichophyticum; tinea profunda","Curated_Disease_Description_Source__c":"ORPHA:397587","Curated_Disease_Description__c":"A rare mycosis characterized by severe, potentially life-threatening dermal and subcutaneous tissue invasion by dermatophytes. Dissemination to lymph nodes is frequent, but the infection may also occasionally spread to the central nervous system. Cutaneous signs and symptoms include erythema, desquamation, itching, nodules, plaques, or ulceration. The majority of deep dermatophytoses develop in immunocompromised patients.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as a Child and as an Adult","SourceID__c":"ORPHA:397587","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0021660","ORPHANET_ID__c":"ORPHA:397587","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Dermatofitosis profunda","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"dermatofitosis profunda","Spanish_GARD_Synonym__c":"dermatofitosis granulomatosa diseminada","Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare mycosis characterized by severe, potentially life-threatening dermal and subcutaneous tissue invasion by dermatophytes. Dissemination to lymph nodes is frequent, but the infection may also occasionally spread to the central nervous system. Cutaneous signs and symptoms include erythema, desquamation, itching, nodules, plaques, or ulceration. The majority of deep dermatophytoses develop in immunocompromised patients.","Curated_Disease_Description_Source__c":"ORPHA:397587","GARD_Synonym__c":"deep seated dermatophytosis; dermatophytic granuloma; dermatophytic mycetoma; dermatophytosis profunda; disseminated granulomatous dermatophytosis; granuloma trichophyticum; tinea profunda","Name":"Deep dermatophytosis","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare mycosis","Tag_Category__c":"Cause","curated_tag_name":"Fungal Infectious Diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:397587"},{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:397587"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/397587","Source__c":"C1395264; MONDO:0021660; ORPHA:397587","Xref__c":"ORPHA:397587"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=235599","Source__c":"C1395264","Xref__c":"MEDGEN:235599"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C35073","Source__c":"C1395264; MONDO:0021660","Xref__c":"C35073"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1395264","Source__c":"C1395264","Xref__c":"C1395264"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0021660","Source__c":"GARD:0021631","Xref__c":"MONDO:0021660"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0032515","Source__c":"C1395264","Xref__c":"HP:0032515"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=266152000","Source__c":"C1395264","Xref__c":"266152000"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare mycosis"]},"synonyms":["deep seated dermatophytosis"," dermatophytic granuloma"," dermatophytic mycetoma"," dermatophytosis profunda"," disseminated granulomatous dermatophytosis"," granuloma trichophyticum"," tinea profunda"]}