{"Name":"Human infection by orthopoxvirus","DiseaseID__c":"GARD:0021822","id":21822,"encodedName":"human-infection-by-orthopoxvirus","IsDeleted":false,"Disease_Name_Full__c":"Human infection by orthopoxvirus","Xref_IDs__c":"C1532229; MEDGEN:734973; MONDO:0018583; ORPHA:438279","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"ORPHA:438279","Disease_Description__c":"A rare viral disease characterized by fever, malaise, lymphadenopathy, and a maculopapular exanthema spreading from the site of infection to other regions of the body. The skin lesions eventually dry out and may leave behind scars. The most relevant orthopox species for human disease after the eradication of the variola virus, which was responsible for smallpox, are the monkeypox virus and the cowpox virus. Infections with these viruses typically take a benign course.","GARD_Name__c":"Human infection by orthopoxvirus","GARD_Synonym__c":"disease caused by orthopoxvirus; orthopoxvirus infection","Curated_Disease_Description_Source__c":"ORPHA:438279","Curated_Disease_Description__c":"A rare viral disease characterized by fever, malaise, lymphadenopathy, and a maculopapular exanthema spreading from the site of infection to other regions of the body. The skin lesions eventually dry out and may leave behind scars. The most relevant orthopox species for human disease after the eradication of the variola virus, which was responsible for smallpox, are the monkeypox virus and the cowpox virus. Infections with these viruses typically take a benign course.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:438279","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0018583","ORPHANET_ID__c":"ORPHA:438279","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Infección humana por orthopoxvirus","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"infección humana por orthopoxvirus","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare viral disease characterized by fever, malaise, lymphadenopathy, and a maculopapular exanthema spreading from the site of infection to other regions of the body. The skin lesions eventually dry out and may leave behind scars. The most relevant orthopox species for human disease after the eradication of the variola virus, which was responsible for smallpox, are the monkeypox virus and the cowpox virus. Infections with these viruses typically take a benign course.","Curated_Disease_Description_Source__c":"ORPHA:438279","GARD_Synonym__c":"disease caused by orthopoxvirus; orthopoxvirus infection","Name":"Human infection by orthopoxvirus","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Viral Disease","Tag_Category__c":"Cause","curated_tag_name":"Viral Infectious Diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:438279"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/438279","Source__c":"C1532229; MONDO:0018583; ORPHA:438279","Xref__c":"ORPHA:438279"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1532229","Source__c":"C1532229","Xref__c":"C1532229"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=734973","Source__c":"C1532229","Xref__c":"MEDGEN:734973"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018583","Source__c":"GARD:0021822","Xref__c":"MONDO:0018583"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=414015000","Source__c":"C1532229","Xref__c":"414015000"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Viral Disease"]},"synonyms":["disease caused by orthopoxvirus"," orthopoxvirus infection"]}