{"Name":"Necrotizing soft tissue infection","DiseaseID__c":"GARD:0021839","id":21839,"encodedName":"necrotizing-soft-tissue-infection","IsDeleted":false,"Disease_Name_Full__c":"Necrotizing soft tissue infection","Xref_IDs__c":"443928008; C2732890; MEDGEN:752585; MONDO:0018602; ORPHA:440368","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"ORPHA:440368","Disease_Description__c":"A rare infectious disease characterized by painful, rapidly progressive infection of deep soft tissue structures. Infections can be mono- or polymicrobial and involve gram-positive cocci, enteric gram-negative bacilli, anaerobes, among others. Fungal infections have also been described in rare cases. Physical examination findings are often subtle and may include erythema, bullae, induration of subcutaneous tissues, and tenderness to palpation.","GARD_Name__c":"Necrotizing soft tissue infection","GARD_Synonym__c":"nsti","Curated_Disease_Description_Source__c":"ORPHA:440368","Curated_Disease_Description__c":"A rare infectious disease characterized by painful, rapidly progressive infection of deep soft tissue structures. Infections can be mono- or polymicrobial and involve gram-positive cocci, enteric gram-negative bacilli, anaerobes, among others. Fungal infections have also been described in rare cases. Physical examination findings are often subtle and may include erythema, bullae, induration of subcutaneous tissues, and tenderness to palpation.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:440368","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0018602","ORPHANET_ID__c":"ORPHA:440368","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Infección necrosante de partes blandas","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"infección necrosante de partes blandas","Spanish_GARD_Synonym__c":"nsti","Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare infectious disease characterized by painful, rapidly progressive infection of deep soft tissue structures. Infections can be mono- or polymicrobial and involve gram-positive cocci, enteric gram-negative bacilli, anaerobes, among others. Fungal infections have also been described in rare cases. Physical examination findings are often subtle and may include erythema, bullae, induration of subcutaneous tissues, and tenderness to palpation.","Curated_Disease_Description_Source__c":"ORPHA:440368","GARD_Synonym__c":"nsti","Name":"Necrotizing soft tissue infection","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Bacterial Infectious Disease","Tag_Category__c":"Cause","curated_tag_name":"Bacterial Infectious Disease"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:440368"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C2732890","Source__c":"C2732890","Xref__c":"C2732890"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=752585","Source__c":"C2732890","Xref__c":"MEDGEN:752585"},{"URL__c":"https://www.orpha.net/en/disease/detail/440368","Source__c":"C2732890; MONDO:0018602; ORPHA:440368","Xref__c":"ORPHA:440368"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=443928008","Source__c":"C2732890; MONDO:0018602","Xref__c":"443928008"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018602","Source__c":"GARD:0021839","Xref__c":"MONDO:0018602"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Bacterial Infectious Disease"]},"synonyms":["nsti"]}