{"Name":"Pheochromocytoma-paraganglioma","DiseaseID__c":"GARD:0022315","id":22315,"encodedName":"pheochromocytoma-paraganglioma","IsDeleted":false,"Disease_Name_Full__c":"Pheochromocytoma-paraganglioma","Xref_IDs__c":"C5681712; MEDGEN:1826130; MONDO:0035540; ORPHA:573163","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0035540","Disease_Description__c":"A rare neuroendocrine tumor arising from chromaffin cells of the adrenal medulla (pheochromocytoma) or from sympathetic and parasympathetic ganglia (paraganglioma). These tumors are most often benign and may produce catecholamines in excess causing hypertension and sometimes severe acute cardiovascular complications.","GARD_Name__c":"Pheochromocytoma-paraganglioma","GARD_Synonym__c":null,"Curated_Disease_Description_Source__c":"MONDO:0035540","Curated_Disease_Description__c":"Pheochromocytomas (often abbreviated as pheos) and paragangliomas (often abbreviated as paras) are rare types of tumors. Pheochromocytomas form in the adrenal glands, while closely related paragangliomas originate from cells of neuronal origin, which can be located throughout the neck, chest, abdomen, or pelvis. These tumors can produce hormones that control the typical body stress reaction and other functions, including heart rate and blood pressure.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:573163","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0035540","ORPHANET_ID__c":"ORPHA:573163","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Feocromocitoma-paraganglioma","Spanish_Description_Source__c":"ORPHA:573163","Spanish_Description__c":"Es un tumor neuroendocrino poco frecuente que surge de las células cromafines de la médula suprarrenal (feocromocitoma) o de los ganglios simpáticos y parasimpáticos (paraganglioma). Estos tumores suelen ser benignos y pueden producir catecolaminas en exceso, lo que causa hipertensión y, en ocasiones, complicaciones cardiovasculares agudas graves.","Spanish_Disease_Name__c":"feocromocitoma-paraganglioma","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:97978","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Pheochromocytomas (often abbreviated as pheos) and paragangliomas (often abbreviated as paras) are rare types of tumors. Pheochromocytomas form in the adrenal glands, while closely related paragangliomas originate from cells of neuronal origin, which can be located throughout the neck, chest, abdomen, or pelvis. These tumors can produce hormones that control the typical body stress reaction and other functions, including heart rate and blood pressure.","Curated_Disease_Description_Source__c":"MONDO:0035540","Name":"Pheochromocytoma-paraganglioma","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Endocrine","Tag_Category__c":"Disease Category;Specialist","category_description":"Endocrine diseases affect hormone production or how the body responds to a specific hormone(s).","curated_tag_name":"Endocrine diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/573163","Source__c":"C5681712; MONDO:0035540; ORPHA:573163","Xref__c":"ORPHA:573163"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1826130","Source__c":"C5681712","Xref__c":"MEDGEN:1826130"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5681712","Source__c":"C5681712","Xref__c":"C5681712"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0035540","Source__c":"GARD:0022315","Xref__c":"MONDO:0035540"},{"URL__c":"https://www.nichd.nih.gov/health/topics/pheochrom"}],"tags":{"Specialist":["Cancer - Oncologist","Endocrine"],"Disease Category":["Cancer","Endocrine"]},"synonyms":[""]}