{"Name":"Familial ventricular tachycardia","DiseaseID__c":"GARD:0002263","id":2263,"encodedName":"familial-ventricular-tachycardia","IsDeleted":false,"Disease_Name_Full__c":"Familial ventricular tachycardia","Xref_IDs__c":"233906007; C0340485; MEDGEN:83309; MONDO:0008648; OMIM:192605","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0008648","Disease_Description__c":"An instance of ventricular tachycardia that is caused by an inherited modification of the individual's genome.","GARD_Name__c":"Familial ventricular tachycardia","GARD_Synonym__c":"hereditary ventricular tachycardia; ventricular tachycardia, familial; ventricular tachycardia, familial polymorphic; ventricular tachycardia, idiopathic","Curated_Disease_Description_Source__c":"MONDO:0008648","Curated_Disease_Description__c":"An instance of ventricular tachycardia that is caused by an inherited modification of the individual's genome.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0008648","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"An instance of ventricular tachycardia that is caused by an inherited modification of the individual's genome.","Curated_Disease_Description_Source__c":"MONDO:0008648","GARD_Synonym__c":"hereditary ventricular tachycardia; ventricular tachycardia, familial; ventricular tachycardia, familial polymorphic; ventricular tachycardia, idiopathic","Name":"Familial ventricular tachycardia","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Clinical Cardiac Electrophysiology","Tag_Category__c":"Specialist","curated_tag_name":"Clinical cardiac electrophysiology"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0340485","Source__c":"C0340485","Xref__c":"C0340485"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=83309","Source__c":"C0340485","Xref__c":"MEDGEN:83309"},{"URL__c":"https://www.omim.org/entry/192605","Source__c":"C0340485; MONDO:0008648","Xref__c":"OMIM:192605"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=233906007","Source__c":"C0340485; MONDO:0008648","Xref__c":"233906007"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0008648","Source__c":"GARD:0002263","Xref__c":"MONDO:0008648"}],"GARD_Disease_Gene__c":[{"GeneSymbol__c":"GNAI2","Gene_Type__c":"protein-coding gene","Causal_Gene__c":true}],"Inheritance__c":["Autosomal dominant"],"GARD_Disease_Feature__c":[{"Provided_By__c":"OMIM:192605","Feature__r":{"HPO_Description__c":"The heart suddenly and unexpectedly stops beating resulting in death within a short time period (generally within 1 h of symptom onset).","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001645","HPO_Synonym__c":"Premature sudden cardiac death; Sudden cardiac death","HPO_Name__c":"Sudden cardiac death","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"OMIM:192605","Feature__r":{"HPO_Description__c":"A conduction block of the right branch of the bundle of His. This manifests as a prolongation of the QRS complex (greater than 0.12 s) with delayed activation of the right ventricle and terminal delay on the EKG.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0011712","HPO_Synonym__c":"Right bundle branch block; Right bundle-branch block","HPO_Name__c":"Complete right bundle branch block","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"OMIM:192605","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Episodes of ventricular tachycardia that have a sudden onset and ending.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0004751","HPO_Synonym__c":"Episodes of ventricular tachycardia","HPO_Name__c":"Paroxysmal ventricular tachycardia","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Clinical Cardiac Electrophysiology"]},"synonyms":["hereditary ventricular tachycardia"," ventricular tachycardia, familial"," ventricular tachycardia, familial polymorphic"," ventricular tachycardia, idiopathic"]}