{"Name":"Ewing sarcoma of bone","DiseaseID__c":"GARD:0023194","id":23194,"encodedName":"ewing-sarcoma-of-bone","IsDeleted":false,"Disease_Name_Full__c":"Ewing sarcoma of bone","Xref_IDs__c":"307608006; C0585474; C4835; DOID:3368; MEDGEN:108438; MONDO:0002625","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":1,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0002625","Disease_Description__c":"A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.","GARD_Name__c":"Ewing sarcoma of bone","GARD_Synonym__c":"bone ewing sarcoma; bone ewing's sarcoma; bone localised ewing sarcoma; bone localised ewing's sarcoma; bone localized ewing sarcoma; bone localized ewing's sarcoma; bone tissue ewing sarcoma; ewing's sarcoma of bone; ewing's sarcoma, osseous; ewing's sarcoma/bone peripheral primitive neuroectodermal tumor; ewing's sarcoma/bone peripheral primitive neuroectodermal tumour; localised skeletal ewing's sarcoma; localized skeletal ewing's sarcoma; osseous ewing's sarcoma; osseous ewing's tumor; osseous ewing's tumour; skeletal ewing's sarcoma; skeletal ewing's tumor; skeletal ewing's tumour","Curated_Disease_Description_Source__c":"MONDO:0002625","Curated_Disease_Description__c":"A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0002625","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A small round cell bone tumor that lacks morphologic, immunohistochemical, and electron microscopic evidence of neuroectodermal differentiation. It represents one of the two ends of the spectrum called Ewing sarcoma/peripheral neuroectodermal tumor. It often affects the diaphysis or metaphyseal-diaphyseal portion of long bones. Clinical findings include pain and a mass in the involved area. fever, anemia, leukocytosis, and an increased sedimentation rate are often seen. X-ray examination reveals osteolytic lesions. The prognosis depends on the stage, anatomic location, and size of the tumor.","Curated_Disease_Description_Source__c":"MONDO:0002625","GARD_Synonym__c":"bone ewing sarcoma; bone ewing's sarcoma; bone localised ewing sarcoma; bone localised ewing's sarcoma; bone localized ewing sarcoma; bone localized ewing's sarcoma; bone tissue ewing sarcoma; ewing's sarcoma of bone; ewing's sarcoma, osseous; ewing's sarcoma/bone peripheral primitive neuroectodermal tumor; ewing's sarcoma/bone peripheral primitive neuroectodermal tumour; localised skeletal ewing's sarcoma; localized skeletal ewing's sarcoma; osseous ewing's sarcoma; osseous ewing's tumor; osseous ewing's tumour; skeletal ewing's sarcoma; skeletal ewing's tumor; skeletal ewing's tumour","Name":"Ewing sarcoma of bone","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C4835","Source__c":"C0585474; MONDO:0002625","Xref__c":"C4835"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A3368","Source__c":"MONDO:0002625","Xref__c":"DOID:3368"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=307608006","Source__c":"C0585474; MONDO:0002625","Xref__c":"307608006"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0585474","Source__c":"C0585474","Xref__c":"C0585474"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=108438","Source__c":"C0585474","Xref__c":"MEDGEN:108438"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0002625","Source__c":"GARD:0023194","Xref__c":"MONDO:0002625"},{"URL__c":"https://www.cancer.gov/types/bone"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["bone ewing sarcoma"," bone ewing's sarcoma"," bone localised ewing sarcoma"," bone localised ewing's sarcoma"," bone localized ewing sarcoma"," bone localized ewing's sarcoma"," bone tissue ewing sarcoma"," ewing's sarcoma of bone"," ewing's sarcoma, osseous"," ewing's sarcoma/bone peripheral primitive neuroectodermal tumor"," ewing's sarcoma/bone peripheral primitive neuroectodermal tumour"," localised skeletal ewing's sarcoma"," localized skeletal ewing's sarcoma"," osseous ewing's sarcoma"," osseous ewing's tumor"," osseous ewing's tumour"," skeletal ewing's sarcoma"," skeletal ewing's tumor"," skeletal ewing's tumour"]}