{"Name":"Pulmonary fibrosis","DiseaseID__c":"GARD:0023241","id":23241,"encodedName":"pulmonary-fibrosis","IsDeleted":false,"Disease_Name_Full__c":"Pulmonary fibrosis","Xref_IDs__c":"51615001; C0034069; C26869; D011658; DOID:3770; HP:0002206; MEDGEN:11028; MONDO:0002771","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":2,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":2,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0002771","Disease_Description__c":"Chronic progressive interstitial lung disorder characterized by the replacement of the lung tissue by connective tissue, leading to progressive dyspnea, respiratory failure, or right heart failure. Causes include chronic inflammatory processes, exposure to environmental irritants, radiation therapy, autoimmune disorders, certain drugs, or it may be idiopathic (no identifiable cause).","GARD_Name__c":"Pulmonary fibrosis","GARD_Synonym__c":"cirrhosis of lung; fibrosis of lung; pulmonary interstitial fibrosis; pulmonary scarring","Curated_Disease_Description_Source__c":"MONDO:0002771","Curated_Disease_Description__c":"Pulmonary fibrosis is a condition in which the tissue deep in your lungs becomes scarred over time. This tissue gets thick and stiff. That makes it hard for you to catch your breath, and your blood may not get enough oxygen.\r\n\r\nCauses of pulmonary fibrosis include environmental pollutants, some medicines, some connective tissue diseases, and interstitial lung disease. Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. In most cases, the cause cannot be found. This is called idiopathic pulmonary fibrosis.\r\n\r\nSymptoms include: shortness of breath, a dry, hacking cough that doesn't get better, fatigue, weight loss for no known reason, aching muscles and joints, clubbing, which is the widening and rounding of the tips of the fingers or toes.\r\n\r\nYour doctor may use your medical history, imaging tests, a biopsy, and lung function tests to diagnose pulmonary fibrosis. There is no cure. Treatments can help with symptoms and improve your quality of life. They include medicines, oxygen therapy, pulmonary rehabilitation, or a lung transplant.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0002771","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Pulmonary fibrosis is a condition in which the tissue deep in your lungs becomes scarred over time. This tissue gets thick and stiff. That makes it hard for you to catch your breath, and your blood may not get enough oxygen.\r\n\r\nCauses of pulmonary fibrosis include environmental pollutants, some medicines, some connective tissue diseases, and interstitial lung disease. Interstitial lung disease is the name for a large group of diseases that inflame or scar the lungs. In most cases, the cause cannot be found. This is called idiopathic pulmonary fibrosis.\r\n\r\nSymptoms include: shortness of breath, a dry, hacking cough that doesn't get better, fatigue, weight loss for no known reason, aching muscles and joints, clubbing, which is the widening and rounding of the tips of the fingers or toes.\r\n\r\nYour doctor may use your medical history, imaging tests, a biopsy, and lung function tests to diagnose pulmonary fibrosis. There is no cure. Treatments can help with symptoms and improve your quality of life. They include medicines, oxygen therapy, pulmonary rehabilitation, or a lung transplant.","Curated_Disease_Description_Source__c":"MONDO:0002771","GARD_Synonym__c":"cirrhosis of lung; fibrosis of lung; pulmonary interstitial fibrosis; pulmonary scarring","Name":"Pulmonary fibrosis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"American Lung Association","Website__c":"https://www.lung.org/"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C26869","Source__c":"C0034069; MONDO:0002771","Xref__c":"C26869"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=51615001","Source__c":"C0034069; MONDO:0002771","Xref__c":"51615001"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C011658","Source__c":"C0034069; MONDO:0002771","Xref__c":"D011658"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=11028","Source__c":"C0034069","Xref__c":"MEDGEN:11028"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0034069","Source__c":"C0034069","Xref__c":"C0034069"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A3770","Source__c":"MONDO:0002771","Xref__c":"DOID:3770"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0002771","Source__c":"GARD:0023241","Xref__c":"MONDO:0002771"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0002206","Source__c":"C0034069","Xref__c":"HP:0002206"},{"URL__c":"https://www.nhlbi.nih.gov/health/idiopathic-pulmonary-fibrosis"},{"URL__c":"https://medlineplus.gov/pulmonaryfibrosis.html"},{"URL__c":"https://www.ncbi.nlm.nih.gov/books/NBK1230","Source__c":"Gene Review","Xref__c":"NBK1230"}],"tags":{},"synonyms":["cirrhosis of lung"," fibrosis of lung"," pulmonary interstitial fibrosis"," pulmonary scarring"]}