{"Name":"Childhood ependymoma","DiseaseID__c":"GARD:0023523","id":23523,"encodedName":"childhood-ependymoma","IsDeleted":false,"Disease_Name_Full__c":"Childhood ependymoma","Xref_IDs__c":"C1851584; C531673; C8578; DOID:5509; MEDGEN:343609; MONDO:0003478","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0003478","Disease_Description__c":"An ependymoma that arises from the central nervous system and occurs during childhood.","GARD_Name__c":"Childhood ependymoma","GARD_Synonym__c":"ependymoma of childhood; paediatric ependymoma; pediatric ependymoma","Curated_Disease_Description_Source__c":"MONDO:0003478","Curated_Disease_Description__c":"Ependymoma is a rare type of tumor that starts in the brain or spinal cord. The brain controls all body functions, such as breathing, heart rate, memory and learning, emotion, and senses. The spinal cord is made up of bundles of nerve fibers that carry messages between the brain and the rest of the body. Together, the brain and spinal cord make up the central nervous system (CNS).\r\n\r\nEpendymomas start when cells called ependymal cells grow without control. Ependymal cells line the ventricles and passageways in the brain and spinal cord and make cerebrospinal fluid (CSF), which acts as a cushion to protect the brain and spinal cord from injury. Ependymomas can spread when the CSF carries ependymoma cells to other parts of the CNS. Ependymomas rarely spread outside the CNS.\r\n\r\nChildren and adults can get ependymoma, but it is more common in young children. This type of tumor accounts for about 9% of all childhood brain and spinal cord tumors, affecting about 200 children per year in the United States.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0003478","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Ependymoma is a rare type of tumor that starts in the brain or spinal cord. The brain controls all body functions, such as breathing, heart rate, memory and learning, emotion, and senses. The spinal cord is made up of bundles of nerve fibers that carry messages between the brain and the rest of the body. Together, the brain and spinal cord make up the central nervous system (CNS).\r\n\r\nEpendymomas start when cells called ependymal cells grow without control. Ependymal cells line the ventricles and passageways in the brain and spinal cord and make cerebrospinal fluid (CSF), which acts as a cushion to protect the brain and spinal cord from injury. Ependymomas can spread when the CSF carries ependymoma cells to other parts of the CNS. Ependymomas rarely spread outside the CNS.\r\n\r\nChildren and adults can get ependymoma, but it is more common in young children. This type of tumor accounts for about 9% of all childhood brain and spinal cord tumors, affecting about 200 children per year in the United States.","Curated_Disease_Description_Source__c":"MONDO:0003478","GARD_Synonym__c":"ependymoma of childhood; paediatric ependymoma; pediatric ependymoma","Name":"Childhood ependymoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Collaborative Ependymoma Research Network","Website__c":"https://cern-foundation.org"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C8578","Source__c":"C1851584; MONDO:0003478","Xref__c":"C8578"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A5509","Source__c":"MONDO:0003478","Xref__c":"DOID:5509"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1851584","Source__c":"C1851584","Xref__c":"C1851584"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C531673","Source__c":"MONDO:0003478","Xref__c":"C531673"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=343609","Source__c":"C1851584","Xref__c":"MEDGEN:343609"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0003478","Source__c":"GARD:0023523","Xref__c":"MONDO:0003478"},{"URL__c":"https://www.cancer.gov/types/brain/patient/childhood-ependymoma"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["ependymoma of childhood"," paediatric ependymoma"," pediatric ependymoma"]}