{"Name":"Childhood leukemia","DiseaseID__c":"GARD:0023954","id":23954,"encodedName":"childhood-leukemia","IsDeleted":false,"Disease_Name_Full__c":"Childhood leukemia","Xref_IDs__c":"C1332977; C4989; DOID:7757; MEDGEN:234132; MONDO:0004355","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0004355","Disease_Description__c":"An acute or chronic leukemia that occurs during childhood.","GARD_Name__c":"Childhood leukemia","GARD_Synonym__c":"childhood leukaemia (disease); childhood leukemia (disease); leukaemia (disease) of childhood; leukemia (disease) of childhood; paediatric leukaemia (disease); pediatric leukemia (disease)","Curated_Disease_Description_Source__c":"MONDO:0004355","Curated_Disease_Description__c":"Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. \r\n\r\nEach type of cell has a different job: 1) White blood cells help your body fight infection 2) Red blood cells deliver oxygen from your lungs to your tissues and organs 3) Platelets help form clots to stop bleeding.\r\n\r\nWhen you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0004355","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. \r\n\r\nEach type of cell has a different job: 1) White blood cells help your body fight infection 2) Red blood cells deliver oxygen from your lungs to your tissues and organs 3) Platelets help form clots to stop bleeding.\r\n\r\nWhen you have leukemia, your bone marrow makes large numbers of abnormal cells. This problem most often happens with white blood cells. These abnormal cells build up in your bone marrow and blood. They crowd out the healthy blood cells and make it hard for your cells and blood to do their work.","Curated_Disease_Description_Source__c":"MONDO:0004355","GARD_Synonym__c":"childhood leukaemia (disease); childhood leukemia (disease); leukaemia (disease) of childhood; leukemia (disease) of childhood; paediatric leukaemia (disease); pediatric leukemia (disease)","Name":"Childhood leukemia","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"The National Children's Cancer Society","Website__c":"https://thenccs.org/"},{"Account_Name__c":"Blood Cancer United","Website__c":"https://bloodcancerunited.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C4989","Source__c":"C1332977; MONDO:0004355","Xref__c":"C4989"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1332977","Source__c":"C1332977","Xref__c":"C1332977"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A7757","Source__c":"MONDO:0004355","Xref__c":"DOID:7757"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=234132","Source__c":"C1332977","Xref__c":"MEDGEN:234132"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0004355","Source__c":"GARD:0023954","Xref__c":"MONDO:0004355"},{"URL__c":"https://medlineplus.gov/childhoodleukemia.html"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["childhood leukaemia (disease)"," childhood leukemia (disease)"," leukaemia (disease) of childhood"," leukemia (disease) of childhood"," paediatric leukaemia (disease)"," pediatric leukemia (disease)"]}