{"Name":"Salivary gland adenosquamous carcinoma","DiseaseID__c":"GARD:0024398","id":24398,"encodedName":"salivary-gland-adenosquamous-carcinoma","IsDeleted":false,"Disease_Name_Full__c":"Salivary gland adenosquamous carcinoma","Xref_IDs__c":"423022290; C1335894; C35737; MEDGEN:277627; MONDO:0006401","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":1,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0006401","Disease_Description__c":"A rare, aggressive carcinoma that arises from the salivary glands. It is characterized by the presence of a squamous and a glandular epithelial component.","GARD_Name__c":"Salivary gland adenosquamous carcinoma","GARD_Synonym__c":"saliva-secreting gland adenosquamous carcinoma","Curated_Disease_Description_Source__c":"MONDO:0006401","Curated_Disease_Description__c":"Salivary cancers form in tissues of salivary glands in the floor of the mouth and throughout the oropharynx, the parotid glands, and the submandibular glands. Cancer of the salivary glands commonly presents with one of several different histologies: mucoepidermoid, adenoid cystic, acinic cell, malignant mixed, squamous or adenocarcinoma. There are two rare histologies, which have much worse prognosis than the standard pathological diagnoses: anaplastic small cell and adenosquamous carcinoma of the salivary glands.\r\n\r\nAdenosquamous carcinoma of the salivary glands is an extremely rare malignant neoplasm that simultaneously arises from surface mucosal epithelium and salivary gland ductal epithelium. The carcinoma shows histopathologic features of both squamous cell carcinoma and adenocarcinoma.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0006401","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Salivary cancers form in tissues of salivary glands in the floor of the mouth and throughout the oropharynx, the parotid glands, and the submandibular glands. Cancer of the salivary glands commonly presents with one of several different histologies: mucoepidermoid, adenoid cystic, acinic cell, malignant mixed, squamous or adenocarcinoma. There are two rare histologies, which have much worse prognosis than the standard pathological diagnoses: anaplastic small cell and adenosquamous carcinoma of the salivary glands.\r\n\r\nAdenosquamous carcinoma of the salivary glands is an extremely rare malignant neoplasm that simultaneously arises from surface mucosal epithelium and salivary gland ductal epithelium. The carcinoma shows histopathologic features of both squamous cell carcinoma and adenocarcinoma.","Curated_Disease_Description_Source__c":"MONDO:0006401","GARD_Synonym__c":"saliva-secreting gland adenosquamous carcinoma","Name":"Salivary gland adenosquamous carcinoma","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C35737","Source__c":"C1335894; MONDO:0006401","Xref__c":"C35737"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C1335894","Source__c":"C1335894","Xref__c":"C1335894"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=277627","Source__c":"C1335894","Xref__c":"MEDGEN:277627"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0006401","Source__c":"GARD:0024398","Xref__c":"MONDO:0006401"},{"URL__c":"https://secure.ssa.gov/apps10/poms.nsf/lnx/0423022290","Xref__c":"423022290"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["saliva-secreting gland adenosquamous carcinoma"]}