{"Name":"Sarcomatoid mesothelioma","DiseaseID__c":"GARD:0024401","id":24401,"encodedName":"sarcomatoid-mesothelioma","IsDeleted":false,"Disease_Name_Full__c":"Sarcomatoid mesothelioma","Xref_IDs__c":"399477001; 423022587; C0334513; C45655; DOID:4488; MEDGEN:137774; MONDO:0006407","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":1,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":1,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0006407","Disease_Description__c":"A diffuse malignant mesothelioma arising from the pleura and less often the peritoneum. It is characterized by the presence of spindle cells. Anaplastic morphologic features and multinucleated malignant cells may also be seen.","GARD_Name__c":"Sarcomatoid mesothelioma","GARD_Synonym__c":"fibrous mesothelioma; fibrous mesothelioma, malignant; malignant fibrous mesothelioma; malignant fibrous mesothelioma (morphologic abnormality); sarcomatoid mesothelioma (morphologic abnormality); spindled mesothelioma","Curated_Disease_Description_Source__c":"MONDO:0006407","Curated_Disease_Description__c":"Sarcomatoid mesothelioma is a rare cell type of cancer caused by asbestos exposure. This condition is a mixed disease with both sarcomatous (affecting connective tissue) and epithelial (related to cells that line the organs) elements. Sarcomatoid cells are recognized by their oval or spindle-like shape.\r\n\r\nSarcomatoid mesothelioma occurs in multiple organ settings, including the uterus, kidneys, lungs, and peritoneum. It accounts for between 10-20% of all mesothelioma diagnoses.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0006407","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Sarcomatoid mesothelioma is a rare cell type of cancer caused by asbestos exposure. This condition is a mixed disease with both sarcomatous (affecting connective tissue) and epithelial (related to cells that line the organs) elements. Sarcomatoid cells are recognized by their oval or spindle-like shape.\r\n\r\nSarcomatoid mesothelioma occurs in multiple organ settings, including the uterus, kidneys, lungs, and peritoneum. It accounts for between 10-20% of all mesothelioma diagnoses.","Curated_Disease_Description_Source__c":"MONDO:0006407","GARD_Synonym__c":"fibrous mesothelioma; fibrous mesothelioma, malignant; malignant fibrous mesothelioma; malignant fibrous mesothelioma (morphologic abnormality); sarcomatoid mesothelioma (morphologic abnormality); spindled mesothelioma","Name":"Sarcomatoid mesothelioma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Mesothelioma Guide","Website__c":"https://www.mesotheliomaguide.com/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=137774","Source__c":"C0334513","Xref__c":"MEDGEN:137774"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0334513","Source__c":"C0334513","Xref__c":"C0334513"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C45655","Source__c":"C0334513; MONDO:0006407","Xref__c":"C45655"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A4488","Source__c":"MONDO:0006407","Xref__c":"DOID:4488"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=399477001","Source__c":"C0334513","Xref__c":"399477001"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0006407","Source__c":"GARD:0024401","Xref__c":"MONDO:0006407"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=54443001","Source__c":"C0334513","Xref__c":"54443001"},{"URL__c":"https://secure.ssa.gov/apps10/poms.nsf/lnx/0423022587","Xref__c":"423022587"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["fibrous mesothelioma"," fibrous mesothelioma, malignant"," malignant fibrous mesothelioma"," malignant fibrous mesothelioma (morphologic abnormality)"," sarcomatoid mesothelioma (morphologic abnormality)"," spindled mesothelioma"]}