{"Name":"Junctional ectopic tachycardia","DiseaseID__c":"GARD:0002706","id":2706,"encodedName":"junctional-ectopic-tachycardia","IsDeleted":false,"Disease_Name_Full__c":"Junctional ectopic tachycardia","Xref_IDs__c":"233901002; 251155001; C0039235; C111646; D013613; HP:0011716; MEDGEN:21066; MONDO:0017989; ORPHA:3283","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":4,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":2,"Description_Source__c":"MONDO:0017989","Disease_Description__c":"His bundle tachycardia is a very rare congenital genetic tachyarrhythmia characterized by incessant tachycardia and high morbidity and mortality.","GARD_Name__c":"Junctional ectopic tachycardia","GARD_Synonym__c":"his bundle (junctional ectopic) tachycardia; his bundle tachycardia; jet","Curated_Disease_Description_Source__c":"MONDO:0017989","Curated_Disease_Description__c":"His bundle tachycardia is a very rare congenital genetic tachyarrhythmia characterized by incessant tachycardia and high morbidity and mortality.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as a Newborn and as an Infant","SourceID__c":"ORPHA:3283","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0017989","ORPHANET_ID__c":"ORPHA:3283","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Taquicardia del haz de his","Spanish_Description_Source__c":"ORPHA:3283","Spanish_Description__c":"Es una taquicardia, congénita y muy poco frecuente, caracterizada por ser incesante y elevada morbimortalidad.","Spanish_Disease_Name__c":"taquicardia del haz de his","Spanish_GARD_Synonym__c":"jet; taquicardia ectópica juntural","Category_Linearization__c":"ORPHA:97929","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"His bundle tachycardia is a very rare congenital genetic tachyarrhythmia characterized by incessant tachycardia and high morbidity and mortality.","Curated_Disease_Description_Source__c":"MONDO:0017989","GARD_Synonym__c":"his bundle (junctional ectopic) tachycardia; his bundle tachycardia; jet","Name":"Junctional ectopic tachycardia","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Genetics","Tag_Category__c":"Cause;Disease Category;Specialist","category_description":"Genetic diseases affect the DNA, or genetic instructions, which directs how tissues, organs, and body systems function.","curated_tag_name":"Genetic diseases"},{"Tag_Name__c":"Cardiology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Clinical Cardiac Electrophysiology","Tag_Category__c":"Specialist","curated_tag_name":"Clinical cardiac electrophysiology"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Infancy","Provided_By__c":"ORPHA:3283"},{"Age_At_Onset__c":"Neonatal","Provided_By__c":"ORPHA:3283"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0039235","Source__c":"C0039235","Xref__c":"C0039235"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=233901002","Source__c":"C0039235; MONDO:0017989","Xref__c":"233901002"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C111646","Source__c":"C0039235; MONDO:0017989","Xref__c":"C111646"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C013613","Source__c":"C0039235; MONDO:0017989","Xref__c":"D013613"},{"URL__c":"https://www.orpha.net/en/disease/detail/3283","Source__c":"C0039235; MONDO:0017989; ORPHA:3283","Xref__c":"ORPHA:3283"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=21066","Source__c":"C0039235","Xref__c":"MEDGEN:21066"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0017989","Source__c":"GARD:0002706","Xref__c":"MONDO:0017989"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0011716","Source__c":"C0039235","Xref__c":"HP:0011716"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=251155001","Source__c":"C0039235","Xref__c":"251155001"}],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:3283","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"A myocardial disorder in which the heart muscle is structurally and functionally abnormal, in the absence of coronary artery disease, hypertension, valvular disease and congenital heart disease sufficient to cause the observed myocardial abnormality.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001638","HPO_Synonym__c":"Disease of the heart muscle","HPO_Name__c":"Cardiomyopathy","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:3283","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Any cardiac rhythm other than the normal sinus rhythm. Such a rhythm may be either of sinus or ectopic origin and either regular or irregular. An arrhythmia may be due to a disturbance in impulse formation or conduction or both.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0011675","HPO_Synonym__c":"Abnormal heart rate; Arrhythmias; Cardiac arrhythmia; Cardiac arrhythmias; Cardiac rhythm disturbances; Heart rhythm disorders; Irregular heart beat; Irregular heartbeat","HPO_Name__c":"Arrhythmia","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:3283","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Junctional ectopic tachycardia (JET) is a unique type of supraventricular arrhythmia defined by narrow QRS complex and atrioventricular (AV) dissociation or retrograde atrial conduction in a 1:1 pattern.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0011716","HPO_Name__c":"Junctional ectopic tachycardia","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:3283","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"A tumor (abnormal growth of tissue) of the heart.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0100544","HPO_Synonym__c":"Cardiac neoplasm; Heart tumor","HPO_Name__c":"Neoplasm of the heart","Feature_System__c":"Cardiovascular System","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Cause":["Genetics"],"Disease Category":["Genetics"],"Specialist":["Genetics","Cardiology","Clinical Cardiac Electrophysiology","Pediatrics"]},"synonyms":["his bundle (junctional ectopic) tachycardia"," his bundle tachycardia"," jet"]}