{"Name":"Kerion celsi","DiseaseID__c":"GARD:0003109","id":3109,"encodedName":"kerion-celsi","IsDeleted":false,"Disease_Name_Full__c":"Kerion celsi","Xref_IDs__c":"19087001; C0276742; MEDGEN:124446; MONDO:0010146; OMIM:275240; ORPHA:499","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":7,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0010146","Disease_Description__c":"A rare inflammatory and suppurating type of tinea capitis, a skin infection caused by <i>Trichophyton</i> or <i>Microsporum</i> fungi, that predominantly affects the scalp and that is characterized by the development of painful crusty lesions covered with follicular pustules and surrounded by erythematous alopecic areas, that can later evolve into abscesses and leave permanent cicatricial alopecia. Lesions can be associated with regional lymphadenopathy.","GARD_Name__c":"Kerion celsi","GARD_Synonym__c":"kerion; suppurative dermatophytosis; suppurative ringworm; tinea imbricata, susceptibility to; tinea kerion","Curated_Disease_Description_Source__c":"MONDO:0010146","Curated_Disease_Description__c":"A rare inflammatory and suppurating type of tinea capitis, a skin infection caused by Trichophyton or Microsporum fungi, that predominantly affects the scalp and that is characterized by the development of painful crusty lesions covered with follicular pustules and surrounded by erythematous alopecic areas, that can later evolve into abscesses and leave permanent cicatricial alopecia. Lesions can be associated with regional lymphadenopathy.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:499","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0010146","ORPHANET_ID__c":"ORPHA:499","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Querión de celso","Spanish_Description_Source__c":"ORPHA:499","Spanish_Description__c":"Es un tipo supurativo e inflamatorio poco frecuente de tiña capitis, una infección de la piel causada por hongos del género <i>Trichophyton</i> o <i>Microsporum</i>, que afecta predominantemente al cuero cabelludo y que se caracteriza por el desarrollo de dolorosas lesiones costrosas con pústulas foliculares, rodeadas de áreas de alopecia eritematosa, que pueden evolucionar más tarde en abscesos y dejar una alopecia cicatricial permanente. Las lesiones pueden estar asociadas a una linfadenopatía regional.","Spanish_Disease_Name__c":"querión de celso","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:89826","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare inflammatory and suppurating type of tinea capitis, a skin infection caused by Trichophyton or Microsporum fungi, that predominantly affects the scalp and that is characterized by the development of painful crusty lesions covered with follicular pustules and surrounded by erythematous alopecic areas, that can later evolve into abscesses and leave permanent cicatricial alopecia. Lesions can be associated with regional lymphadenopathy.","Curated_Disease_Description_Source__c":"MONDO:0010146","GARD_Synonym__c":"kerion; suppurative dermatophytosis; suppurative ringworm; tinea imbricata, susceptibility to; tinea kerion","Name":"Kerion celsi","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Dermatology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Skin diseases, or integumentary system diseases, affect the skin, hair, nails, sweat glands, or oil glands.","curated_tag_name":"Skin diseases"},{"Tag_Name__c":"Rare mycosis","Tag_Category__c":"Cause","curated_tag_name":"Fungal Infectious Diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:499"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/499","Source__c":"C0276742; MONDO:0010146; ORPHA:499","Xref__c":"ORPHA:499"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=19087001","Source__c":"C0276742; MONDO:0010146","Xref__c":"19087001"},{"URL__c":"https://www.omim.org/entry/275240","Source__c":"C0276742; MONDO:0010146","Xref__c":"OMIM:275240"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0276742","Source__c":"C0276742","Xref__c":"C0276742"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=124446","Source__c":"C0276742","Xref__c":"MEDGEN:124446"},{"URL__c":"https://hpo.jax.org/browse/term/HP:6000424","Source__c":"C0276742","Xref__c":"HP:6000424"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0010146","Source__c":"GARD:0003109","Xref__c":"MONDO:0010146"}],"Inheritance__c":["Autosomal recessive"],"GARD_Disease_Feature__c":[{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Enlargement (swelling) of a lymph node.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002716","HPO_Synonym__c":"Lymph node hyperplasia; Swollen lymph nodes","HPO_Name__c":"Lymphadenopathy","Feature_System__c":"Cardiovascular System; Immune System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"Migraine is a chronic neurological disorder characterized by episodic attacks of headache and associated symptoms.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0002076","HPO_Synonym__c":"Intermittent migraine headaches; Migraine; Migraine headache; Migraine headaches","HPO_Name__c":"Migraine","Feature_System__c":"Nervous System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Occasional (5-29%)","Feature__r":{"HPO_Description__c":"Pain in muscle.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0003326","HPO_Synonym__c":"Muscle ache; Muscle pain","HPO_Name__c":"Myalgia","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"A noncongenital process of hair loss, which may progress to partial or complete baldness.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001596","HPO_Synonym__c":"Hair loss","HPO_Name__c":"Alopecia","Feature_System__c":"Skin System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"The presence of inflammation of the skin. That is, an abnormality of the skin resulting from the local accumulation of fluid, plasma proteins, and leukocytes.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0011123","HPO_Synonym__c":"Abnormal tendency to infections of the skin; Inflammatory abnormality of the skin; Skin inflammation","HPO_Name__c":"Inflammatory abnormality of the skin","Feature_System__c":"Skin System; Immune System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"Infections of the skin that happen multiple times.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001581","HPO_Synonym__c":"Recurrent cutaneous infections; Recurrent skin infections; Skin infections, recurrent","HPO_Name__c":"Recurrent skin infections","Feature_System__c":"Skin System; Immune System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Very frequent (80-99%)","Feature__r":{"HPO_Description__c":"An increased susceptibility to cutaneous abscess formation, as manifested by a medical history of recurrent cutaneous abscesses.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0100838","HPO_Name__c":"Recurrent cutaneous abscess formation","Feature_System__c":"Skin System; Immune System","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"ORPHA:499","HPO_Frequency__c":"Frequent (30-79%)","Feature__r":{"HPO_Description__c":"Body temperature elevated above the normal range.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001945","HPO_Synonym__c":"Fever; Hyperthermia; Pyrexia","HPO_Name__c":"Fever","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Account":["Dermatology"],"Disease Category":["Dermatology"],"Specialist":["Dermatology","Pediatrics"],"Cause":["Rare mycosis"]},"synonyms":["kerion"," suppurative dermatophytosis"," suppurative ringworm"," tinea imbricata, susceptibility to"," tinea kerion"]}