{"Name":"Childhood-onset schizophrenia","DiseaseID__c":"GARD:0004766","id":4766,"encodedName":"childhood-onset-schizophrenia","IsDeleted":false,"Disease_Name_Full__c":"Childhood-onset schizophrenia","Xref_IDs__c":"1335862003; C0036346; C35004; MEDGEN:48576; MONDO:0957430; ORPHA:641496","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":2,"Description_Source__c":null,"Disease_Description__c":null,"GARD_Name__c":"Childhood-onset schizophrenia","GARD_Synonym__c":"childhood schizophrenia; cos - childhood-onset schizophrenia; veos - very early-onset schizophrenia; very early-onset schizophrenia","Curated_Disease_Description_Source__c":null,"Curated_Disease_Description__c":"This rare brain and mental health disease appears before age 13. It most often results in early developmental challenges, including processing, learning, language, and physical skills. Children often have trouble with social communication and getting along with others. Before clear psychotic symptoms appear, many children experience auditory hallucinations, or hearing sounds or voices that are not there. Visual or touch hallucinations are less common. Other neurodevelopmental diseases, such as autism spectrum disorders and attention deficit hyperactivity disorder (ADHD), often occur at the same time. The overall impact on development is major, and the course of the disease is more severe than when schizophrenia starts in adulthood.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as a Child and as a Teenager","SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0957430","ORPHANET_ID__c":"ORPHA:641496","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Esquizofrenia de inicio en la infancia","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"esquizofrenia de inicio en la infancia","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"This rare brain and mental health disease appears before age 13. It most often results in early developmental challenges, including processing, learning, language, and physical skills. Children often have trouble with social communication and getting along with others. Before clear psychotic symptoms appear, many children experience auditory hallucinations, or hearing sounds or voices that are not there. Visual or touch hallucinations are less common. Other neurodevelopmental diseases, such as autism spectrum disorders and attention deficit hyperactivity disorder (ADHD), often occur at the same time. The overall impact on development is major, and the course of the disease is more severe than when schizophrenia starts in adulthood.","GARD_Synonym__c":"childhood schizophrenia; cos - childhood-onset schizophrenia; veos - very early-onset schizophrenia; very early-onset schizophrenia","Name":"Childhood-onset schizophrenia","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"},{"Tag_Name__c":"Psychiatry","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:641496"},{"Age_At_Onset__c":"Adolescent","Provided_By__c":"ORPHA:641496"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=48576","Source__c":"C0036346","Xref__c":"MEDGEN:48576"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0036346","Source__c":"C0036346","Xref__c":"C0036346"},{"URL__c":"https://www.orpha.net/en/disease/detail/641496","Source__c":"MONDO:0957430","Xref__c":"ORPHA:641496"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=1335862003","Source__c":"C0036346","Xref__c":"1335862003"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0957430","Source__c":"GARD:0004766","Xref__c":"MONDO:0957430"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C35004","Source__c":"C0036346","Xref__c":"C35004"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C012561","Source__c":"C0036346","Xref__c":"D012561"}],"tags":{"Disease Category":["Neurology"],"Specialist":["Neurology","Psychiatry","Pediatrics"]},"synonyms":["childhood schizophrenia"," cos - childhood-onset schizophrenia"," veos - very early-onset schizophrenia"," very early-onset schizophrenia"]}