{"Name":"Testicular seminoma","DiseaseID__c":"GARD:0004792","id":4792,"encodedName":"testicular-seminoma","IsDeleted":false,"Disease_Name_Full__c":"Testicular seminoma","Xref_IDs__c":"255107005; C5551428; C7328; DOID:5842; HP:0100617; MEDGEN:1790467; MONDO:0003669; ORPHA:842","USA_Estimate__c":"200,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"800,000 to 5,000,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0003669","Disease_Description__c":"A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.","GARD_Name__c":"Testicular seminoma","GARD_Synonym__c":"seminoma of testis; seminoma of the testis; seminoma testis; seminomatous germ cell tumor of testis; seminomatous germ cell tumour of testis; testicular seminoma (disease); testicular seminoma pure; testicular seminomatous germ cell tumor; testicular seminomatous germ cell tumour; testis seminoma","Curated_Disease_Description_Source__c":"MONDO:0003669","Curated_Disease_Description__c":"A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"200,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:842","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0003669","ORPHANET_ID__c":"ORPHA:842","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Tumor testicular de células germinales seminomatoso","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"tumor testicular de células germinales seminomatoso","Spanish_GARD_Synonym__c":"seminoma de los testículos; seminoma testicular; tumor de células germinales seminomatoso de los testículos","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A malignant germ cell tumor arising from the testis. It is believed that it is derived from the sexually undifferentiated embryonic gonad. Treatment with radiotherapy is highly successful when the tumor is diagnosed in localized stages, which represents the majority of presentations of seminoma.","Curated_Disease_Description_Source__c":"MONDO:0003669","GARD_Synonym__c":"seminoma of testis; seminoma of the testis; seminoma testis; seminomatous germ cell tumor of testis; seminomatous germ cell tumour of testis; testicular seminoma (disease); testicular seminoma pure; testicular seminomatous germ cell tumor; testicular seminomatous germ cell tumour; testis seminoma","Name":"Testicular seminoma","Curated_USA_Estimate__c":"200,000","estimateUsa":"200,000"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Urogenital Disorders","Tag_Category__c":"Disease Category","category_description":"Urinary and reproductive diseases affect the kidneys, ureters, bladder, urethra, or the reproductive organs.","curated_tag_name":"Urinary and reproductive diseases"},{"Tag_Name__c":"Urologist","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:842"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0004792","Source__c":"RareSource"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=255107005","Source__c":"C5551428; MONDO:0003669","Xref__c":"255107005"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5551428","Source__c":"C5551428","Xref__c":"C5551428"},{"URL__c":"https://www.orpha.net/en/disease/detail/842","Source__c":"C5551428; MONDO:0003669; ORPHA:842","Xref__c":"ORPHA:842"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C7328","Source__c":"C5551428; MONDO:0003669","Xref__c":"C7328"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A5842","Source__c":"MONDO:0003669","Xref__c":"DOID:5842"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1790467","Source__c":"C5551428","Xref__c":"MEDGEN:1790467"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0100617","Source__c":"C5551428","Xref__c":"HP:0100617"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0003669","Source__c":"GARD:0004792","Xref__c":"MONDO:0003669"}],"GARD_Disease_Gene__c":[{"GeneSymbol__c":"KIT","GHR_URL__c":"https://medlineplus.gov/genetics/gene/kit","Gene_Type__c":"protein-coding gene","Causal_Gene__c":true}],"tags":{"Specialist":["Cancer - Oncologist","Urologist"],"Disease Category":["Cancer","Urogenital Disorders"]},"synonyms":["seminoma of testis"," seminoma of the testis"," seminoma testis"," seminomatous germ cell tumor of testis"," seminomatous germ cell tumour of testis"," testicular seminoma (disease)"," testicular seminoma pure"," testicular seminomatous germ cell tumor"," testicular seminomatous germ cell tumour"," testis seminoma"]}