{"Name":"Soft tissue sarcoma","DiseaseID__c":"GARD:0004898","id":4898,"encodedName":"soft-tissue-sarcoma","IsDeleted":false,"Disease_Name_Full__c":"Soft tissue sarcoma","Xref_IDs__c":"424952003; C4551687; C9306; HP:0030448; MEDGEN:1642116; MONDO:0018078; ORPHA:3394","USA_Estimate__c":"50,000","No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":3,"World_Estimate__c":"80,000 to 800,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":3,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0018078","Disease_Description__c":"A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones.","GARD_Name__c":"Soft tissue sarcoma","GARD_Synonym__c":"connective tissue sarcoma; malignant mesenchymal tumor; malignant mesenchymal tumour; non-rhabdo. soft tissue sarcoma; sarcoma of soft tissue; sarcoma of the soft tissue; soft part sarcoma; soft tissue sarcomas","Curated_Disease_Description_Source__c":"GARD:0004898","Curated_Disease_Description__c":"Soft tissue sarcoma is a form of cancer that occurs due to abnormal and uncontrolled cell growth of the \"soft tissues\" of the body. These tissues connect, support and surround other body parts and may include muscle, fat, blood vessels, lymph vessels, nerves, tendons and the lining of joints. Many people with early Soft tissue sarcoma have no signs or symptoms of the condition. When present, symptoms depend on the location and size of the tumor but may include a palpable lump under the skin, pain, or difficulty breathing. Most cases occur sporadically in people with little to no family history of the condition. People who have previously received radiation therapy and those with certain inherited disorders (such as Gorlin syndrome, Gardner syndrome, Li-Fraumeni syndrome, Tuberous sclerosis, neurofibromatosis type 1, and Werner syndrome) have an increased risk of developing a Soft tissue sarcoma.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"50,000","Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:3394","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0018078","ORPHANET_ID__c":"ORPHA:3394","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Sarcoma de partes blandas","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"sarcoma de partes blandas","Spanish_GARD_Synonym__c":"sarcoma de tejidos blandos; tumor maligno de tejidos blandos; tumor mesenquimal maligno","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Soft tissue sarcoma is a form of cancer that occurs due to abnormal and uncontrolled cell growth of the \"soft tissues\" of the body. These tissues connect, support and surround other body parts and may include muscle, fat, blood vessels, lymph vessels, nerves, tendons and the lining of joints. Many people with early Soft tissue sarcoma have no signs or symptoms of the condition. When present, symptoms depend on the location and size of the tumor but may include a palpable lump under the skin, pain, or difficulty breathing. Most cases occur sporadically in people with little to no family history of the condition. People who have previously received radiation therapy and those with certain inherited disorders (such as Gorlin syndrome, Gardner syndrome, Li-Fraumeni syndrome, Tuberous sclerosis, neurofibromatosis type 1, and Werner syndrome) have an increased risk of developing a Soft tissue sarcoma.","Curated_Disease_Description_Source__c":"GARD:0004898","GARD_Synonym__c":"connective tissue sarcoma; malignant mesenchymal tumor; malignant mesenchymal tumour; non-rhabdo. soft tissue sarcoma; sarcoma of soft tissue; sarcoma of the soft tissue; soft part sarcoma; soft tissue sarcomas","Name":"Soft tissue sarcoma","Curated_USA_Estimate__c":"50,000","estimateUsa":"50,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Sarcoma UK","Website__c":"https://sarcoma.org.uk/"},{"Account_Name__c":"Sarcoma Foundation of America","Website__c":"https://www.curesarcoma.org/"},{"Account_Name__c":"The Limb Preservation Foundation","Website__c":"http://limbpreservation.org/"},{"Account_Name__c":"Sarcoma Alliance for Research through Collaboration","Website__c":"https://sarctrials.org"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1642116","Source__c":"C4551687","Xref__c":"MEDGEN:1642116"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=424952003","Source__c":"C4551687; MONDO:0018078","Xref__c":"424952003"},{"URL__c":"https://www.orpha.net/en/disease/detail/3394","Source__c":"C4551687; MONDO:0018078","Xref__c":"ORPHA:3394"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C9306","Source__c":"C4551687; MONDO:0018078","Xref__c":"C9306"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C4551687","Source__c":"C4551687","Xref__c":"C4551687"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0018078","Source__c":"GARD:0004898","Xref__c":"MONDO:0018078"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0030448","Source__c":"C4551687","Xref__c":"HP:0030448"},{"URL__c":"https://www.cancer.gov/types/soft-tissue-sarcoma/patient/adult-soft-tissue-treatment-pdq"},{"URL__c":"https://www.cancer.gov/types/soft-tissue-sarcoma"},{"URL__c":"https://medlineplus.gov/softtissuesarcoma.html"}],"tags":{"Specialist":["Cancer - Oncologist"],"Disease Category":["Cancer"]},"synonyms":["connective tissue sarcoma"," malignant mesenchymal tumor"," malignant mesenchymal tumour"," non-rhabdo. soft tissue sarcoma"," sarcoma of soft tissue"," sarcoma of the soft tissue"," soft part sarcoma"," soft tissue sarcomas"]}