{"Name":"Actinomycotic infection","DiseaseID__c":"GARD:0005728","id":5728,"encodedName":"actinomycotic-infection","IsDeleted":false,"Disease_Name_Full__c":"Actinomycotic infection","Xref_IDs__c":"11817007; A42; C0001261; C34350; D000196; DOID:8478; MEDGEN:1733; MONDO:0005631; ORPHA:457095","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0005631","Disease_Description__c":"Actinomycosis is a chronic bacterial infection that commonly affects the face and neck. It is usually caused by an anaerobic bacteria called Actinomyces israelii. Actinomyces are normal inhabitants of the mouth, gastrointestinal tract, and female genital tract, and do not cause an infection unless there is a break in the skin or mucosa. The infection usually occurs in the face and neck, but can sometimes occur in the chest, abdomen, pelvis, or other areas of the body. The infection is not contagious.","GARD_Name__c":"Actinomycotic infection","GARD_Synonym__c":"actinomyces infection; actinomycosis; actinomycotic madura foot; actinomycotic mycetema; actinomycotic mycetoma of foot; anaerobic actinomyces infection; madura foot due to actinomadura","Curated_Disease_Description_Source__c":"GARD:0005728","Curated_Disease_Description__c":"Actinomycosis is a bacterial infection that occurs most often in the face and neck. Symptoms of Actinomycosis include a neck mass, jaw or face pain, and formation of pockets of pus (abscess). When Actinomycosis occurs in other parts of the body, symptoms can include cough, chest or stomach pain, fever, and weight loss. It is usually caused by bacteria called Actinomyces israelii. These bacteria are found normally in the mouth, gastrointestinal tract, and female genital tract, and do not cause an infection unless there is a break in the skin or mucosa. The infection is not contagious. Actinomycosis is diagnosed based on the history and clinical exam, and through specific laboratory tests.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:457095","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0005631","ORPHANET_ID__c":"ORPHA:457095","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Actinomicosis","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"actinomicosis","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Actinomycosis is a bacterial infection that occurs most often in the face and neck. Symptoms of Actinomycosis include a neck mass, jaw or face pain, and formation of pockets of pus (abscess). When Actinomycosis occurs in other parts of the body, symptoms can include cough, chest or stomach pain, fever, and weight loss. It is usually caused by bacteria called Actinomyces israelii. These bacteria are found normally in the mouth, gastrointestinal tract, and female genital tract, and do not cause an infection unless there is a break in the skin or mucosa. The infection is not contagious. Actinomycosis is diagnosed based on the history and clinical exam, and through specific laboratory tests.","Curated_Disease_Description_Source__c":"GARD:0005728","GARD_Synonym__c":"actinomyces infection; actinomycosis; actinomycotic madura foot; actinomycotic mycetema; actinomycotic mycetoma of foot; anaerobic actinomyces infection; madura foot due to actinomadura","Name":"Actinomycotic infection","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Rare Bacterial Infectious Disease","Tag_Category__c":"Cause","curated_tag_name":"Bacterial Infectious Disease"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:457095"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A8478","Source__c":"MONDO:0005631","Xref__c":"DOID:8478"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0001261","Source__c":"C0001261","Xref__c":"C0001261"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C34350","Source__c":"C0001261; MONDO:0005631","Xref__c":"C34350"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C000196","Source__c":"C0001261; MONDO:0005631","Xref__c":"D000196"},{"URL__c":"https://www.orpha.net/en/disease/detail/457095","Source__c":"C0001261; MONDO:0005631; ORPHA:457095","Xref__c":"ORPHA:457095"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1733","Source__c":"C0001261","Xref__c":"MEDGEN:1733"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=11817007","Source__c":"C0001261","Xref__c":"11817007"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0005631","Source__c":"GARD:0005728","Xref__c":"MONDO:0005631"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/A42","Source__c":"MONDO:0005631","Xref__c":"A42"}],"tags":{"Disease Category":["Infectious Disease"],"Specialist":["Infectious Disease","Pediatrics"],"Cause":["Rare Bacterial Infectious Disease"]},"synonyms":["actinomyces infection"," actinomycosis"," actinomycotic madura foot"," actinomycotic mycetema"," actinomycotic mycetoma of foot"," anaerobic actinomyces infection"," madura foot due to actinomadura"]}